{"id":35522129,"url":"https://github.com/alwinw/epoc-aki","last_synced_at":"2026-01-04T00:01:54.367Z","repository":{"id":46211597,"uuid":"230730224","full_name":"alwinw/epoc-aki","owner":"alwinw","description":"📈 Evaluation of the Predictive value of short-term Oliguria and minor Creatinine increases for Acute Kidney Injury in ICU","archived":false,"fork":false,"pushed_at":"2022-07-31T10:08:42.000Z","size":88396,"stargazers_count":9,"open_issues_count":1,"forks_count":1,"subscribers_count":0,"default_branch":"master","last_synced_at":"2025-09-05T02:18:08.141Z","etag":null,"topics":["acute-kidney-failure","aki","bookdown","classification","creatinine","kidney","logistic-regression","oliguria","r","rmd","statistical-analysis","time-series"],"latest_commit_sha":null,"homepage":"","language":"R","has_issues":true,"has_wiki":null,"has_pages":null,"mirror_url":null,"source_name":null,"license":"gpl-3.0","status":null,"scm":"git","pull_requests_enabled":true,"icon_url":"https://github.com/alwinw.png","metadata":{"files":{"readme":"README.md","changelog":null,"contributing":null,"funding":null,"license":"LICENSE","code_of_conduct":null,"threat_model":null,"audit":null,"citation":"CITATION.cff","codeowners":null,"security":null,"support":null,"governance":null,"roadmap":null,"authors":null,"dei":null,"publiccode":null,"codemeta":null,"zenodo":null}},"created_at":"2019-12-29T09:38:26.000Z","updated_at":"2024-12-25T20:55:02.000Z","dependencies_parsed_at":"2022-09-25T05:41:19.081Z","dependency_job_id":null,"html_url":"https://github.com/alwinw/epoc-aki","commit_stats":null,"previous_names":[],"tags_count":6,"template":false,"template_full_name":null,"purl":"pkg:github/alwinw/epoc-aki","repository_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/alwinw%2Fepoc-aki","tags_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/alwinw%2Fepoc-aki/tags","releases_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/alwinw%2Fepoc-aki/releases","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/alwinw%2Fepoc-aki/manifests","owner_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/alwinw","download_url":"https://codeload.github.com/alwinw/epoc-aki/tar.gz/refs/heads/master","sbom_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/alwinw%2Fepoc-aki/sbom","scorecard":null,"host":{"name":"GitHub","url":"https://github.com","kind":"github","repositories_count":286080680,"owners_count":28195652,"icon_url":"https://github.com/github.png","version":null,"created_at":"2022-05-30T11:31:42.601Z","updated_at":"2022-07-04T15:15:14.044Z","status":"online","status_checked_at":"2026-01-03T02:00:06.471Z","response_time":75,"last_error":null,"robots_txt_status":"success","robots_txt_updated_at":"2025-07-24T06:49:26.215Z","robots_txt_url":"https://github.com/robots.txt","online":true,"can_crawl_api":true,"host_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub","repositories_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories","repository_names_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repository_names","owners_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners"}},"keywords":["acute-kidney-failure","aki","bookdown","classification","creatinine","kidney","logistic-regression","oliguria","r","rmd","statistical-analysis","time-series"],"created_at":"2026-01-04T00:01:50.187Z","updated_at":"2026-01-04T00:01:54.361Z","avatar_url":"https://github.com/alwinw.png","language":"R","funding_links":[],"categories":["R"],"sub_categories":[],"readme":"# The EPOC-AKI Study \u003cimg src='doc/images/logo.png' align=\"right\" height=\"138.5\" /\u003e\n\nEvaluation of the Predictive value of short-term Oliguria and minor Creatinine increases for Acute Kidney Injury (AKI) in ICU\n\n- Austin Health ResearchFest 2020: [Virtual Poster Presentation](https://doi.org/10.6084/m9.figshare.13055699.v1)\n\n- Journal of Critical Care article: [Small, short-term, point-of-care creatinine changes as predictors of acute kidney injury in critically ill patients](https://doi.org/10.1016/j.jcrc.2022.154097)\n\n## Data Overview\n\n### Definitions\n\n![Data Overview](/doc/images/overview.png)\n\nChanges in Creatinine Episodes:\n\n- Creatinine change during episode (µmol/L): Δcr\n- Duration of creatinine change episode (hrs): Δt\u003csub\u003ecr_ch\u003c/sub\u003e = T\u003csub\u003ei\u003c/sub\u003e - (T\u003csub\u003ei\u003c/sub\u003e - δt)\n- Time between end of cr change epis and AKI (hrs or NA): Δt\u003csub\u003eaki\u003c/sub\u003e = T\u003csub\u003eAKI\u003c/sub\u003e - T\u003csub\u003ei\u003c/sub\u003e\n\nOliguria Episodes:\n\n- Time Oliguria identified: T\u003csub\u003eolig\u003c/sub\u003e = T\u003csub\u003e0\u003c/sub\u003e\n- Time Oliguria episode started: T\u003csub\u003eolig_4\u003c/sub\u003e = T\u003csub\u003e0\u003c/sub\u003e - 4\n- Time between olig epis and AKI (hrs or NA): Δt\u003csub\u003eaki\u003c/sub\u003e - T\u003csub\u003eAKI\u003c/sub\u003e - T\u003csub\u003e0\u003c/sub\u003e\n\n### Exploration\n\n![Data Exploration](/doc/images/heatmap_AKI_ICU.png)\n\nExample: Significant difference in creatinine changes 8 \u003c Δt\u003csub\u003ecr_ch\u003c/sub\u003e \u003c 12 between 'No AKI' and 't\u003csub\u003eAKI\u003c/sub\u003e in 4-8 hrs'\n\n## Running\n\n1. Clone the repository and open the R project file `epoc-aki.Rproj` with RStudio\n\n    ```bash\n    git clone git@github.com:alwinw/epoc-api.git\n    ```\n\n2. Preview the relevant `bookdown` file\n\n   - Option 1: Open the file directly in RStudio\n\n      1. Open up the bookdown index, e.g. `doc/full/index.Rmd`\n      2. In RStudio run `Addins` \u003e `Preview Book`, or from the console run\n\n        ```R\n        bookdown::serve_book()\n        ```\n\n   - Option 2: Run `serve_book` from the console\n\n        ```R\n        bookdown::serve_book(dir = \"doc/full/\")\n        ```\n\n3. Preview the bookdown site at `http://localhost:4321/` or `http://127.0.0.1:4321/`\n\n## Contributors\n\nAlwin Wang and Lisa Toh\n\n## Acknowledgements\n\n## Activity\n\n![GitHub commit activity](https://img.shields.io/github/commit-activity/m/alwinw/epoc-aki?style=flat-square)\n![GitHub last commit](https://img.shields.io/github/last-commit/alwinw/epoc-aki?style=flat-square)\n![Visits](https://badges.pufler.dev/visits/alwinw/epoc-aki?style=flat-square\u0026label=visits)\n![GitHub repo size in bytes](https://img.shields.io/github/repo-size/alwinw/epoc-aki?style=flat-square)\n![Total Lines](https://img.shields.io/tokei/lines/github/alwinw/epoc-aki?style=flat-square)\n\n## License\n\n[![GitHub](https://img.shields.io/github/license/alwinw/epoc-aki?style=flat-square)](LICENSE)\n\n- [GPL-3.0 License](https://opensource.org/licenses/GPL-3.0)\n- Copyright 2020 © [Alwin Wang](https://github.com/alwinw) and [Lisa Toh](https://github.com/lymt)\n","project_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Falwinw%2Fepoc-aki","html_url":"https://awesome.ecosyste.ms/projects/github.com%2Falwinw%2Fepoc-aki","lists_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Falwinw%2Fepoc-aki/lists"}