{"id":13752567,"url":"https://github.com/aqlaboratory/rgn2","last_synced_at":"2025-04-25T15:33:11.036Z","repository":{"id":83565503,"uuid":"198262356","full_name":"aqlaboratory/rgn2","owner":"aqlaboratory","description":null,"archived":false,"fork":false,"pushed_at":"2023-11-28T17:16:23.000Z","size":17905,"stargazers_count":98,"open_issues_count":4,"forks_count":29,"subscribers_count":11,"default_branch":"master","last_synced_at":"2024-08-03T09:04:09.063Z","etag":null,"topics":[],"latest_commit_sha":null,"homepage":null,"language":"Python","has_issues":true,"has_wiki":null,"has_pages":null,"mirror_url":null,"source_name":null,"license":null,"status":null,"scm":"git","pull_requests_enabled":true,"icon_url":"https://github.com/aqlaboratory.png","metadata":{"files":{"readme":"README.md","changelog":null,"contributing":null,"funding":null,"license":null,"code_of_conduct":null,"threat_model":null,"audit":null,"citation":null,"codeowners":null,"security":null,"support":null,"governance":null,"roadmap":null,"authors":null,"dei":null,"publiccode":null,"codemeta":null}},"created_at":"2019-07-22T16:23:41.000Z","updated_at":"2024-06-26T17:16:07.000Z","dependencies_parsed_at":null,"dependency_job_id":"62977e10-7b05-4bf4-adbf-6f4d4a73c2a0","html_url":"https://github.com/aqlaboratory/rgn2","commit_stats":null,"previous_names":[],"tags_count":0,"template":false,"template_full_name":null,"repository_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/aqlaboratory%2Frgn2","tags_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/aqlaboratory%2Frgn2/tags","releases_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/aqlaboratory%2Frgn2/releases","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/aqlaboratory%2Frgn2/manifests","owner_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/aqlaboratory","download_url":"https://codeload.github.com/aqlaboratory/rgn2/tar.gz/refs/heads/master","host":{"name":"GitHub","url":"https://github.com","kind":"github","repositories_count":224007933,"owners_count":17240294,"icon_url":"https://github.com/github.png","version":null,"created_at":"2022-05-30T11:31:42.601Z","updated_at":"2022-07-04T15:15:14.044Z","host_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub","repositories_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories","repository_names_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repository_names","owners_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners"}},"keywords":[],"created_at":"2024-08-03T09:01:07.617Z","updated_at":"2024-11-10T20:10:50.597Z","avatar_url":"https://github.com/aqlaboratory.png","language":"Python","funding_links":[],"categories":["Ranked by starred repositories"],"sub_categories":[],"readme":"# RGN2\n\nThis is the reference implementation of recurrent geometric network-2 (RGN2), described in the paper _Single-sequence protein structure prediction using a language model and deep learning_.\n\n**Note:** We recommend using RGN2 primarily for prediction of orphan or de novo proteins. For proteins with known homologs we suggest using\n[AlphaFold2](https://colab.research.google.com/github/sokrypton/ColabFold/blob/main/AlphaFold2.ipynb) or \n[OpenFold](https://colab.research.google.com/github/aqlaboratory/openfold/blob/main/notebooks/OpenFold.ipynb).\n\n## Usage\nUse the [RGN2 Colab notebook](https://colab.research.google.com/github/aqlaboratory/rgn2/blob/master/rgn2_prediction.ipynb) to predict the 3D structures for orphan or de novo protein sequences.\n\n\n## Reference\n[Single-sequence protein structure prediction using a language model and deep learning, Nature Biotechnology 2022](https://rdcu.be/cWPgh)\n","project_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Faqlaboratory%2Frgn2","html_url":"https://awesome.ecosyste.ms/projects/github.com%2Faqlaboratory%2Frgn2","lists_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Faqlaboratory%2Frgn2/lists"}