{"id":22059804,"url":"https://github.com/armandfs/genom-comp-fp","last_synced_at":"2026-07-04T06:06:49.434Z","repository":{"id":210825828,"uuid":"727537355","full_name":"ArmandFS/genom-comp-fp","owner":"ArmandFS","description":"This project leverages computational techniques to analyze genomic data from eukaryotic cells. 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This project leverages computational techniques to analyze genomic data from eukaryotic cells. The program calculates open reading frames (ORFs) from FASTA files, outputs genomic data, sequences, statistics, and includes a Hidden Markov Model (HMM) with an interactive GUI built using `ipywidgets`.\n\n## 🧬 Introduction 🧬 \n\nGenomic computation combines biology and computational methods to provide deep insights into genomic data. This project aims to:\n\n- Calculate open reading frames (ORFs) from eukaryotic cell genomic data.\n- Output comprehensive genomic data, sequences, and statistics.\n- Utilize a Hidden Markov Model (HMM) for detailed DNA sequence analysis.\n- Provide an intuitive GUI with `ipywidgets` for user interaction.\n\n## ✨ Features\n\n- **Open Reading Frame Calculation**: Identify and extract ORFs from eukaryotic cell genomic data.\n- **Hidden Markov Model (HMM)**: Advanced DNA sequence analysis using HMM.\n- **Interactive GUI**: User-friendly interface powered by `ipywidgets`.\n- **Detailed Reports**: Generate and view genomic data, sequences, and statistical analysis.\n\n## 🎉 Example\n\n1. **Upload a FASTA file**:\n   - Click on the \"Upload\" button in the GUI and select your FASTA file.\n\n2. **Calculate ORFs**:\n   - Click on the \"Calculate ORFs\" button to process the uploaded file.\n\n3. **Analyze with HMM**:\n   - Click on the \"Run HMM Analysis\" button to analyze the sequences.\n\n4. **View Results**:\n   - Results, including genomic data, sequences, and statistics, will be displayed in the GUI.\n\n## 🗂️ Project Structure\n\n```plaintext\ngenom-comp-fp/\n│\n├── data/                   # Sample data files\n├── src/                    # Source code\n│   ├── orf_calculation.py  # ORF calculation module\n│   ├── hmm_analysis.py     # HMM analysis module\n│   ├── gui.py              # GUI module using ipywidgets\n│   └── main.py             # Main script\n├── tests/                  # Test files\n├── README.md               # This README file\n├── requirements.txt        # Python dependencies\n\n```\n","project_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Farmandfs%2Fgenom-comp-fp","html_url":"https://awesome.ecosyste.ms/projects/github.com%2Farmandfs%2Fgenom-comp-fp","lists_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Farmandfs%2Fgenom-comp-fp/lists"}