{"id":25864149,"url":"https://github.com/bradleyedelman/combo-window","last_synced_at":"2026-05-09T20:23:06.785Z","repository":{"id":257594241,"uuid":"858751822","full_name":"BradleyEdelman/COMBO-Window","owner":"BradleyEdelman","description":"The COMBO Window is a chronic cranial implant for mice, designed for long-term, multimodal neural recordings.","archived":false,"fork":false,"pushed_at":"2025-02-12T08:22:30.000Z","size":1599,"stargazers_count":0,"open_issues_count":0,"forks_count":0,"subscribers_count":1,"default_branch":"main","last_synced_at":"2025-02-12T09:40:09.014Z","etag":null,"topics":["3d-printing","behavior-analysis","cranial-implant-design","electrophysiology","functional-ultrasound","neuroimaging","time-series-analysis","two-photon-imaging"],"latest_commit_sha":null,"homepage":"","language":"MATLAB","has_issues":true,"has_wiki":null,"has_pages":null,"mirror_url":null,"source_name":null,"license":null,"status":null,"scm":"git","pull_requests_enabled":true,"icon_url":"https://github.com/BradleyEdelman.png","metadata":{"files":{"readme":"README.md","changelog":null,"contributing":null,"funding":null,"license":null,"code_of_conduct":null,"threat_model":null,"audit":null,"citation":null,"codeowners":null,"security":null,"support":null,"governance":null,"roadmap":null,"authors":null,"dei":null,"publiccode":null,"codemeta":null}},"created_at":"2024-09-17T13:26:05.000Z","updated_at":"2025-02-12T08:24:23.000Z","dependencies_parsed_at":null,"dependency_job_id":"ec57cb8e-8957-4889-bb76-150e8bcfc4a8","html_url":"https://github.com/BradleyEdelman/COMBO-Window","commit_stats":null,"previous_names":["bradleyedelman/combo-window"],"tags_count":0,"template":false,"template_full_name":null,"repository_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/BradleyEdelman%2FCOMBO-Window","tags_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/BradleyEdelman%2FCOMBO-Window/tags","releases_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/BradleyEdelman%2FCOMBO-Window/releases","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/BradleyEdelman%2FCOMBO-Window/manifests","owner_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/BradleyEdelman","download_url":"https://codeload.github.com/BradleyEdelman/COMBO-Window/tar.gz/refs/heads/main","host":{"name":"GitHub","url":"https://github.com","kind":"github","repositories_count":241444028,"owners_count":19963749,"icon_url":"https://github.com/github.png","version":null,"created_at":"2022-05-30T11:31:42.601Z","updated_at":"2022-07-04T15:15:14.044Z","host_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub","repositories_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories","repository_names_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repository_names","owners_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners"}},"keywords":["3d-printing","behavior-analysis","cranial-implant-design","electrophysiology","functional-ultrasound","neuroimaging","time-series-analysis","two-photon-imaging"],"created_at":"2025-03-02T00:36:44.367Z","updated_at":"2026-05-09T20:23:06.693Z","avatar_url":"https://github.com/BradleyEdelman.png","language":"MATLAB","funding_links":[],"categories":[],"sub_categories":[],"readme":"# COMBO Window\n\nThis repository contains **3D printer (and laser cutter) files**, as well as **analysis and plotting code** associated with the validation of the **COMBO Window**—a chronic cranial implant for multiscale circuit interrogation in mice.\n\n## 📄 Related Publication\n\n### **The COMBO Window: A Chronic Cranial Implant for Multiscale Circuit Interrogation in Mice**  \n**B. J. Edelman \u0026 D. Siegenthaler et al., PLOS Biology, 2024**  \n- Introduces **a novel cranial implant** that enables **long-term, multimodal neural recordings** in head-fixed moving mice.  \n- **Key contributions:**\n  - **Supports multiple imaging modalities** (two-photonimaging, functional ultrasound imaging, electrophysiology).  \n  - Enables **stable, chronic recordings months after implantation** while maintaining high-quality optical access.  \n  - **Designed for easy fabrication and open-source sharing** using 3D printing and laser cutting.  \n\n📄 [Read the full paper](https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002664)\n\n---\n\n## 📂 Open-Source Data  \nThe full dataset used for validation is available on **Edmond (MPG Open Science)**:  \n\n[View Data on Edmond](https://edmond.mpg.de/dataset.xhtml?persistentId=doi:10.17617/3.5KYYHK)  \n\n---\n\n## 🛠️ 3D Printer Files \u0026 Plotting Code  \nThe **3D models, laser cutter files, and plotting code** are hosted on **Zenodo**:  \n\n[Download files from Zenodo](https://zenodo.org/records/11092491)  \n\n---\n\n## Summary  \nThe **COMBO Window** is an **open-source cranial implant** designed for long-term **multimodal neural recordings in mice**. This repository provides:\n- **3D printer \u0026 laser cutter files** for fabrication.  \n- **Analysis \u0026 plotting scripts** for validation data.  \n- **Open-access datasets \u0026 code** for reproducibility and further development.\n","project_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fbradleyedelman%2Fcombo-window","html_url":"https://awesome.ecosyste.ms/projects/github.com%2Fbradleyedelman%2Fcombo-window","lists_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fbradleyedelman%2Fcombo-window/lists"}