{"id":32591033,"url":"https://github.com/certara/simcyp-r-scripts","last_synced_at":"2026-07-06T05:33:53.123Z","repository":{"id":300049190,"uuid":"715614877","full_name":"certara/Simcyp-R-Scripts","owner":"certara","description":"Simcyp R example scripts","archived":false,"fork":false,"pushed_at":"2026-02-12T11:04:51.000Z","size":91238,"stargazers_count":1,"open_issues_count":0,"forks_count":0,"subscribers_count":1,"default_branch":"main","last_synced_at":"2026-07-06T05:33:29.432Z","etag":null,"topics":["pbpk","pbpk-modeling"],"latest_commit_sha":null,"homepage":"","language":"R","has_issues":true,"has_wiki":null,"has_pages":null,"mirror_url":null,"source_name":null,"license":null,"status":null,"scm":"git","pull_requests_enabled":true,"icon_url":"https://github.com/certara.png","metadata":{"files":{"readme":"README.md","changelog":null,"contributing":null,"funding":null,"license":null,"code_of_conduct":null,"threat_model":null,"audit":null,"citation":null,"codeowners":null,"security":null,"support":null,"governance":null,"roadmap":null,"authors":null,"dei":null,"publiccode":null,"codemeta":null,"zenodo":null,"notice":null,"maintainers":null,"copyright":null,"agents":null,"dco":null,"cla":null}},"created_at":"2023-11-07T13:53:16.000Z","updated_at":"2026-03-09T09:14:11.000Z","dependencies_parsed_at":"2025-09-08T10:20:21.525Z","dependency_job_id":null,"html_url":"https://github.com/certara/Simcyp-R-Scripts","commit_stats":null,"previous_names":["certara/simcyp-r-scripts"],"tags_count":2,"template":false,"template_full_name":null,"purl":"pkg:github/certara/Simcyp-R-Scripts","repository_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/certara%2FSimcyp-R-Scripts","tags_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/certara%2FSimcyp-R-Scripts/tags","releases_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/certara%2FSimcyp-R-Scripts/releases","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/certara%2FSimcyp-R-Scripts/manifests","owner_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/certara","download_url":"https://codeload.github.com/certara/Simcyp-R-Scripts/tar.gz/refs/heads/main","sbom_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/certara%2FSimcyp-R-Scripts/sbom","scorecard":null,"host":{"name":"GitHub","url":"https://github.com","kind":"github","repositories_count":286080680,"owners_count":35179683,"icon_url":"https://github.com/github.png","version":null,"created_at":"2022-05-30T11:31:42.601Z","updated_at":"2026-05-26T15:22:16.424Z","status":"online","status_checked_at":"2026-07-06T02:00:07.184Z","response_time":106,"last_error":null,"robots_txt_status":"success","robots_txt_updated_at":"2025-07-24T06:49:26.215Z","robots_txt_url":"https://github.com/robots.txt","online":true,"can_crawl_api":true,"host_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub","repositories_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories","repository_names_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repository_names","owners_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners"}},"keywords":["pbpk","pbpk-modeling"],"created_at":"2025-10-30T01:54:56.720Z","updated_at":"2026-07-06T05:33:53.119Z","avatar_url":"https://github.com/certara.png","language":"R","funding_links":[],"categories":[],"sub_categories":[],"readme":"# Simcyp R Example Scripts\n\n## Description \nA package to support R script interactions with the Simcyp simulator (V23-V25). Provides functions to initialise Simcyp, load and modify workspaces and interrogate results.  \n\n\n## System Requirements \n\n* Windows 10 \n* Simcyp Simulator license\n* R \u003e= 4.5.1\n\n## Installation  \n\nThe Simcyp R Package requires additional package dependencies, which can first be installed from CRAN using the following command: \n\n```r\ninstall.packages(c(\"Rcpp\", \"xml2\", \"RcppThread\", \"R.utils\", \"RSQLite\", \"DBI\", \"rlang\", \"tibble\", \"fs\", \"PKNCA\", \"dplyr\", \"stringr\", \"ggplot2\", \"pracma\", \"rstudioapi\")) \n```\n\nThe Simcyp R package is distributed from Simcyp support via a download link and can be requested from simcyp.support@certara.com.\n\nFirst, download the package archive file from the Simcyp download portal, then navigate to RStudio \\\u003e Tools \\\u003e Install Packages. In the \"Install from:\" dropdown selection, change to \"Package archive file\" and select the Simcyp R package `.zip` file in your file explorer.\n\n\nThe current Released Version  of the Simcyp R package is `Simcyp_25.0.44.zip`.\n\n## Examples \n\nNavigate to one of the example folders within the repository to view usage details.\n\n## Support\n\nPlease email simcyp.support@certara.com for any queries.\n\n## Learning material:  \nIf you are a Simcyp license members, E-Learning videos can be viewed via your members area.\n\nOther learning videos can be found on YouTube:  \n\n* [Simcyp R package overview](https://youtu.be/9KuWlyrPMko?si=nuXK41YlvI4IWx28)\n* [Simcyp R package overview v21](https://youtu.be/htlC2EvDWTk?si=NEKdw5i6u3oCI43S)\n* [Summary statistics and ribbon plots](https://youtu.be/qn5YVLGPis4?si=7N85NKH8S229tITR)\n* [Forest plots](https://youtu.be/bi6M6IpCYdc?si=gzMcdbEolDqc7hpl)\n\n## Publications:  \n* [SimRFlow: An R-based workflow for automated high-throughput PBPK simulation with the Simcyp® simulator](https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.929200/full)\n* [Using the Simcyp R Package for PBPK Simulation Workflows With the Simcyp Simulator](https://pubmed.ncbi.nlm.nih.gov/40179011/)\n","project_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fcertara%2Fsimcyp-r-scripts","html_url":"https://awesome.ecosyste.ms/projects/github.com%2Fcertara%2Fsimcyp-r-scripts","lists_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fcertara%2Fsimcyp-r-scripts/lists"}