{"id":20424992,"url":"https://github.com/databio/epihet","last_synced_at":"2025-08-02T05:11:36.117Z","repository":{"id":84917649,"uuid":"84873955","full_name":"databio/epihet","owner":"databio","description":"Calculating epigenetic heterogeneity","archived":false,"fork":false,"pushed_at":"2019-01-23T16:50:52.000Z","size":501,"stargazers_count":1,"open_issues_count":1,"forks_count":1,"subscribers_count":18,"default_branch":"master","last_synced_at":"2025-03-05T04:44:27.204Z","etag":null,"topics":[],"latest_commit_sha":null,"homepage":"","language":"R","has_issues":true,"has_wiki":null,"has_pages":null,"mirror_url":null,"source_name":null,"license":null,"status":null,"scm":"git","pull_requests_enabled":true,"icon_url":"https://github.com/databio.png","metadata":{"files":{"readme":"README.md","changelog":"NEWS","contributing":null,"funding":null,"license":null,"code_of_conduct":null,"threat_model":null,"audit":null,"citation":null,"codeowners":null,"security":null,"support":null,"governance":null,"roadmap":null,"authors":null,"dei":null,"publiccode":null,"codemeta":null}},"created_at":"2017-03-13T20:57:56.000Z","updated_at":"2019-02-04T09:55:09.000Z","dependencies_parsed_at":"2023-03-13T03:21:32.937Z","dependency_job_id":null,"html_url":"https://github.com/databio/epihet","commit_stats":null,"previous_names":[],"tags_count":0,"template":false,"template_full_name":null,"purl":"pkg:github/databio/epihet","repository_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/databio%2Fepihet","tags_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/databio%2Fepihet/tags","releases_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/databio%2Fepihet/releases","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/databio%2Fepihet/manifests","owner_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/databio","download_url":"https://codeload.github.com/databio/epihet/tar.gz/refs/heads/master","sbom_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/databio%2Fepihet/sbom","host":{"name":"GitHub","url":"https://github.com","kind":"github","repositories_count":267030826,"owners_count":24024233,"icon_url":"https://github.com/github.png","version":null,"created_at":"2022-05-30T11:31:42.601Z","updated_at":"2022-07-04T15:15:14.044Z","status":"online","status_checked_at":"2025-07-25T02:00:09.625Z","response_time":70,"last_error":null,"robots_txt_status":"success","robots_txt_updated_at":"2025-07-24T06:49:26.215Z","robots_txt_url":"https://github.com/robots.txt","online":true,"can_crawl_api":true,"host_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub","repositories_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories","repository_names_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repository_names","owners_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners"}},"keywords":[],"created_at":"2024-11-15T07:11:54.054Z","updated_at":"2025-07-25T16:34:29.902Z","avatar_url":"https://github.com/databio.png","language":"R","funding_links":[],"categories":[],"sub_categories":[],"readme":"# Epihet: Epigenetic heterogeneity from DNA methylation\n[![Build Status](https://travis-ci.org/databio/epihet.svg?branch=master)](https://travis-ci.org/databio/epihet)\n\n`Epihet` calculates a the PIM score, which measures the epigenetic heterogeneity in a bisulfite sequencing sample. Under the assumption that a homogeneous sample will have mostly CpGs with either 100% or 0% DNA methylation, it follows that the proportion of sites that differ from these two extremes can be used as a measure of sample heterogeneity.\n\n\n\n### Installing\n\nInstall the development version of epihet directly from GitHub:\n\n```{r}\n\ndevtools::install_github(\"databio/epihet\")\n\n```\n\n\n\nor locally after downloading/cloning the source code:\n\n```{r}\n\ninstall.packages(\"path/to/epihet/directory\", repos=NULL, type=\"source\")\n\n```\n\n### How to use\n\nPlease see the [vignettes](/vignettes) for details.\n","project_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fdatabio%2Fepihet","html_url":"https://awesome.ecosyste.ms/projects/github.com%2Fdatabio%2Fepihet","lists_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fdatabio%2Fepihet/lists"}