{"id":22731056,"url":"https://github.com/genentech/reglm","last_synced_at":"2025-04-14T00:32:42.697Z","repository":{"id":198788125,"uuid":"699144851","full_name":"Genentech/regLM","owner":"Genentech","description":"Toolkit for training hyenaDNA-based autoregressive language models on DNA sequences.","archived":false,"fork":false,"pushed_at":"2024-06-17T17:34:14.000Z","size":4346,"stargazers_count":24,"open_issues_count":0,"forks_count":0,"subscribers_count":7,"default_branch":"main","last_synced_at":"2024-09-26T02:01:41.067Z","etag":null,"topics":[],"latest_commit_sha":null,"homepage":"","language":"Jupyter Notebook","has_issues":true,"has_wiki":null,"has_pages":null,"mirror_url":null,"source_name":null,"license":"mit","status":null,"scm":"git","pull_requests_enabled":true,"icon_url":"https://github.com/Genentech.png","metadata":{"files":{"readme":"README.md","changelog":null,"contributing":null,"funding":null,"license":"LICENSE.txt","code_of_conduct":null,"threat_model":null,"audit":null,"citation":null,"codeowners":null,"security":null,"support":null,"governance":null,"roadmap":null,"authors":"AUTHORS.md","dei":null,"publiccode":null,"codemeta":null}},"created_at":"2023-10-02T02:39:49.000Z","updated_at":"2024-08-03T20:00:56.000Z","dependencies_parsed_at":null,"dependency_job_id":"ad9350f7-e672-449e-adc5-3bd702a90e53","html_url":"https://github.com/Genentech/regLM","commit_stats":null,"previous_names":["genentech/reglm"],"tags_count":0,"template":false,"template_full_name":null,"repository_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/Genentech%2FregLM","tags_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/Genentech%2FregLM/tags","releases_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/Genentech%2FregLM/releases","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/Genentech%2FregLM/manifests","owner_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/Genentech","download_url":"https://codeload.github.com/Genentech/regLM/tar.gz/refs/heads/main","host":{"name":"GitHub","url":"https://github.com","kind":"github","repositories_count":229117070,"owners_count":18022819,"icon_url":"https://github.com/github.png","version":null,"created_at":"2022-05-30T11:31:42.601Z","updated_at":"2022-07-04T15:15:14.044Z","host_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub","repositories_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories","repository_names_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repository_names","owners_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners"}},"keywords":[],"created_at":"2024-12-10T19:19:17.399Z","updated_at":"2024-12-10T19:19:18.132Z","avatar_url":"https://github.com/Genentech.png","language":"Jupyter Notebook","funding_links":[],"categories":[],"sub_categories":[],"readme":"\n# regLM\nregLM is a toolkit for training hyenaDNA-based autoregressive language models on DNA sequences and generating novel regulatory elements.\n\n![regLM schematic](fig1.png)\n\n## Documentation\n\n[Documentation](https://genentech.github.io/regLM)\n\n## Tutorials\n\n[Tutorials](tutorials)\n\n## Installation\n\n### 1. Install HyenaDNA\nTo use regLM, first install HyenaDNA from GitHub following the instructions: https://github.com/HazyResearch/hyena-dna\n\n### 2. Install regLM\n```\ngit clone https://github.com/Genentech/regLM.git\ncd regLM\npip install .\n```\n\n## Publication\n\nhttps://genome.cshlp.org/content/early/2024/09/24/gr.279142.124.abstract\n\nLal, A., Garfield, D., Biancalani, T., \u0026 Eraslan, G. (2024). Designing realistic regulatory DNA with autoregressive language models. Genome Research.\n","project_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fgenentech%2Freglm","html_url":"https://awesome.ecosyste.ms/projects/github.com%2Fgenentech%2Freglm","lists_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fgenentech%2Freglm/lists"}