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Generation Sequencing","Genomic data wrangling","医疗领域","Python","Packages","Ranked by starred repositories","Biomedical Research \u0026 Drug Discovery"],"sub_categories":["Data Analysis","Mendelian randomization in _cis_","Bioinformatics"],"readme":"# Hail\n\n[![Zulip](https://img.shields.io/badge/zulip-join_chat-brightgreen.svg)](https://hail.zulipchat.com?utm_source=badge\u0026utm_medium=badge\u0026utm_campaign=pr-badge) [![DOI](https://zenodo.org/badge/45069467.svg)](https://zenodo.org/badge/latestdoi/45069467) [![PyPI version](https://badge.fury.io/py/hail.svg)](https://badge.fury.io/py/hail)\n\n[Hail](https://hail.is) is an open-source, general-purpose, Python-based data analysis tool with additional data types and methods for working with genomic data.\n\nHail is built to scale and has first-class support for multi-dimensional structured data, like the genomic data in a genome-wide association study (GWAS).\n\nHail is exposed as a Python library, using primitives for distributed queries and linear algebra implemented in Scala, [Spark](https://spark.apache.org/docs/latest/index.html), and increasingly C++.\n\nSee the [documentation](https://hail.is/docs/0.2/) for more info on using Hail.\n\n### Community\n\nHail has been widely adopted in academia and industry, including as the analysis platform for the [genome aggregation database](https://gnomad.broadinstitute.org) and [UK Biobank rapid GWAS](https://www.nealelab.is/uk-biobank). Learn more about [Hail-powered science](https://hail.is/references.html).\n\n### Contribute\n\nIf you'd like to discuss or contribute to the development of methods or infrastructure, please:\n\n- see the [For Software Developers](https://hail.is/docs/0.2/getting_started_developing.html) section of the installation guide for info on compiling Hail\n- chat with us about development in our [Zulip chatroom](https://hail.zulipchat.com)\n- visit the [Development Forum](https://dev.hail.is) for longer-form discussions\n\u003c!--- - read [this post]() (coming soon!) for tips on submitting a successful Pull Request to our repository ---\u003e\n\nHail uses a continuous deployment approach to software development, which means we frequently add new features. We update users about changes to Hail via the [Discussion Forum](https://discuss.hail.is). We recommend creating an account on the Discussion Forum so that you can subscribe to these updates as well.\n\n### Maintainer\n\nHail is maintained by a team in the [Neale lab](https://nealelab.is/) at the [Stanley Center for Psychiatric Research](https://www.broadinstitute.org/stanley) of the [Broad Institute of MIT and Harvard](https://www.broadinstitute.org) and the [Analytic and Translational Genetics Unit](https://www.atgu.mgh.harvard.edu/) of [Massachusetts General Hospital](https://www.massgeneral.org/).\n\nContact the Hail team at \u003ccode\u003e\u003ca href=\"mailto:hail@broadinstitute.org\"\u003ehail@broadinstitute.org\u003c/a\u003e\u003c/code\u003e.\n\n### Citing Hail\n\nIf you use Hail for published work, please cite the software. You can get a\ncitation for the version of Hail you installed by executing:\n\n```python\nimport hail as hl\nprint(hl.citation())\n```\n\nWhich will look like:\n\n```\nHail Team. Hail 0.2.13-81ab564db2b4. https://github.com/hail-is/hail/releases/tag/0.2.13.\n```\n\n##### Acknowledgements\n\nThe Hail team has several sources of funding at the Broad Institute:\n- The Stanley Center for Psychiatric Research, which together with Neale Lab has provided an incredibly supportive and stimulating home.\n- Principal Investigators Benjamin Neale and Daniel MacArthur, whose scientific leadership has been essential for solving the right problems.\n- Jeremy Wertheimer, whose strategic advice and generous philanthropy have been essential for growing the impact of Hail.\n\nWe are grateful for generous support from:\n- The National Institute of Diabetes and Digestive and Kidney Diseases\n- The National Institute of Mental Health\n- The National Human Genome Research Institute\n- The Chan Zuckerberg Initiative\n\nWe would like to thank \u003ca href=\"https://zulipchat.com/\"\u003eZulip\u003c/a\u003e for supporting\nopen-source by providing free hosting, and YourKit, LLC for generously providing\nfree licenses for \u003ca href=\"https://www.yourkit.com/java/profiler/\"\u003eYourKit Java\nProfiler\u003c/a\u003e for open-source development.\n\n\u003cimg src=\"https://www.yourkit.com/images/yklogo.png\" align=\"right\" /\u003e\n","project_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fhail-is%2Fhail","html_url":"https://awesome.ecosyste.ms/projects/github.com%2Fhail-is%2Fhail","lists_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fhail-is%2Fhail/lists"}