{"id":29139613,"url":"https://github.com/leooojr/divv","last_synced_at":"2026-05-17T06:32:17.351Z","repository":{"id":284783085,"uuid":"940623373","full_name":"LeoooJR/DIVV","owner":"LeoooJR","description":"Differential Investigation of Variability in Variants","archived":false,"fork":false,"pushed_at":"2025-08-27T17:17:42.000Z","size":7662,"stargazers_count":0,"open_issues_count":2,"forks_count":0,"subscribers_count":1,"default_branch":"main","last_synced_at":"2025-08-28T02:04:57.486Z","etag":null,"topics":["bioinformatics","python","variant-analysis","variant-calling","variants","vcf","vcf-comparison"],"latest_commit_sha":null,"homepage":"","language":"C","has_issues":true,"has_wiki":null,"has_pages":null,"mirror_url":null,"source_name":null,"license":null,"status":null,"scm":"git","pull_requests_enabled":true,"icon_url":"https://github.com/LeoooJR.png","metadata":{"files":{"readme":"README.md","changelog":null,"contributing":null,"funding":null,"license":null,"code_of_conduct":null,"threat_model":null,"audit":null,"citation":null,"codeowners":null,"security":null,"support":null,"governance":null,"roadmap":null,"authors":null,"dei":null,"publiccode":null,"codemeta":null,"zenodo":null}},"created_at":"2025-02-28T14:01:24.000Z","updated_at":"2025-07-17T09:30:19.000Z","dependencies_parsed_at":null,"dependency_job_id":"55ba75fe-6ab4-4340-a5f9-f3a4fa98d787","html_url":"https://github.com/LeoooJR/DIVV","commit_stats":null,"previous_names":["leooojr/vcfdelta","leooojr/divv"],"tags_count":0,"template":false,"template_full_name":null,"purl":"pkg:github/LeoooJR/DIVV","repository_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/LeoooJR%2FDIVV","tags_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/LeoooJR%2FDIVV/tags","releases_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/LeoooJR%2FDIVV/releases","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/LeoooJR%2FDIVV/manifests","owner_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/LeoooJR","download_url":"https://codeload.github.com/LeoooJR/DIVV/tar.gz/refs/heads/main","sbom_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/LeoooJR%2FDIVV/sbom","scorecard":null,"host":{"name":"GitHub","url":"https://github.com","kind":"github","repositories_count":286080680,"owners_count":33129247,"icon_url":"https://github.com/github.png","version":null,"created_at":"2022-05-30T11:31:42.601Z","updated_at":"2026-05-17T06:27:06.342Z","status":"ssl_error","status_checked_at":"2026-05-17T06:26:59.432Z","response_time":107,"last_error":"SSL_read: unexpected eof while reading","robots_txt_status":"success","robots_txt_updated_at":"2025-07-24T06:49:26.215Z","robots_txt_url":"https://github.com/robots.txt","online":false,"can_crawl_api":true,"host_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub","repositories_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories","repository_names_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repository_names","owners_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners"}},"keywords":["bioinformatics","python","variant-analysis","variant-calling","variants","vcf","vcf-comparison"],"created_at":"2025-06-30T15:37:32.844Z","updated_at":"2026-05-17T06:32:17.335Z","avatar_url":"https://github.com/LeoooJR.png","language":"C","funding_links":[],"categories":[],"sub_categories":[],"readme":"# DIVV\n\n\u003ccenter\u003e\u003cimg src=\"logo.png\" width=\"500\" height=\"500\"\u003e\u003c/center\u003e\u003cbr\u003e\n\n![Static Badge](https://img.shields.io/badge/python-3.10%2B-yellow?label=python\u0026labelColor=grey\u0026color=yellow)\n![Static Badge](https://img.shields.io/badge/htslib-1.21-grey?color=brightgreen)\n![GitHub last commit](https://img.shields.io/github/last-commit/LeoooJR/DIVV)\n\n## :bookmark_tabs: Table of Contents \u003ca name=\"table\"\u003e\n- [About](#about)\n- [Getting Started](#getting-started)\n- [Contacts](#contacts)\n\n## :pencil: About The Project \u003ca name=\"about\"\u003e\n\n\u003cp align=\"justify\"\u003e\nDIVV is a software tool designed for comparing two VCF files that have been generated from panel sequencing.\u003cbr\u003e\nIt leverages the CyVCF2 library, which is actively maintained, providing superior VCF file parsing compared to PyVCF. Additionally, tasks are parallelized to enhance efficiency. Moreover, a dynamic report is generated, offering users an optimized and user-friendly visualization of the results.\n\u003c/p\u003e\n\n## :rocket: Getting Started \u003ca name=\"getting-started\"\u003e\n\n```bash\n# Clone the repository\ngit clone https://github.com/LeoooJR/DIVV.git\n\n# Changed directory to the cloned repository\ncd DIVV\n```\n\n### :computer: Local installation\n\n```bash\n# Compile htslib\n./install.sh ./src\n\n# Get help about DIVV\npython src/main.py --help\n\n# Compare VCF files\npython src/main.py --vcfs \u003cVCF1\u003e \u003cVCF2\u003e --report --output \u003cPATH\u003e\n```\n\n### :whale2: Using docker\n\n```bash\n# Build the image\ndocker build -t divv .\n\n# Run the container\ndocker run --rm divv --vcfs \u003cVCF1\u003e \u003cVCF2\u003e --report --output \u003cPATH\u003e\n\n# Get help about DIVV\ndocker run --rm divv --help\n```\n\n## 🗨️ Contacts \u003ca name=\"contacts\"\u003e\u003c/a\u003e\n\nFor questions, feel free to reach out to the maintainers through GitHub or connect on LinkedIn.\n\n[Back to top](#top)\n","project_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fleooojr%2Fdivv","html_url":"https://awesome.ecosyste.ms/projects/github.com%2Fleooojr%2Fdivv","lists_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fleooojr%2Fdivv/lists"}