{"id":18322930,"url":"https://github.com/liyigerry/gp120","last_synced_at":"2026-02-10T01:01:26.007Z","repository":{"id":129748498,"uuid":"130810850","full_name":"liyigerry/gp120","owner":"liyigerry","description":"Data, methods and code for research on the molecular dynamics of HIV glycoprotein gp120","archived":false,"fork":false,"pushed_at":"2020-03-21T11:58:48.000Z","size":480793,"stargazers_count":2,"open_issues_count":0,"forks_count":0,"subscribers_count":1,"default_branch":"master","last_synced_at":"2025-07-28T22:45:07.027Z","etag":null,"topics":["gp120","markov-state-model","molecular-dynamics","simulation"],"latest_commit_sha":null,"homepage":"","language":null,"has_issues":true,"has_wiki":null,"has_pages":null,"mirror_url":null,"source_name":null,"license":null,"status":null,"scm":"git","pull_requests_enabled":true,"icon_url":"https://github.com/liyigerry.png","metadata":{"files":{"readme":"README.md","changelog":null,"contributing":null,"funding":null,"license":null,"code_of_conduct":null,"threat_model":null,"audit":null,"citation":null,"codeowners":null,"security":null,"support":null,"governance":null,"roadmap":null,"authors":null,"dei":null,"publiccode":null,"codemeta":null}},"created_at":"2018-04-24T07:02:46.000Z","updated_at":"2022-03-13T03:30:07.000Z","dependencies_parsed_at":"2023-06-26T02:04:54.965Z","dependency_job_id":null,"html_url":"https://github.com/liyigerry/gp120","commit_stats":null,"previous_names":[],"tags_count":0,"template":false,"template_full_name":null,"purl":"pkg:github/liyigerry/gp120","repository_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/liyigerry%2Fgp120","tags_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/liyigerry%2Fgp120/tags","releases_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/liyigerry%2Fgp120/releases","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/liyigerry%2Fgp120/manifests","owner_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/liyigerry","download_url":"https://codeload.github.com/liyigerry/gp120/tar.gz/refs/heads/master","sbom_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/liyigerry%2Fgp120/sbom","scorecard":null,"host":{"name":"GitHub","url":"https://github.com","kind":"github","repositories_count":286080680,"owners_count":29287694,"icon_url":"https://github.com/github.png","version":null,"created_at":"2022-05-30T11:31:42.601Z","updated_at":"2026-02-09T21:57:15.303Z","status":"ssl_error","status_checked_at":"2026-02-09T21:57:11.537Z","response_time":56,"last_error":"SSL_connect returned=1 errno=0 peeraddr=140.82.121.6:443 state=error: unexpected eof while reading","robots_txt_status":"success","robots_txt_updated_at":"2025-07-24T06:49:26.215Z","robots_txt_url":"https://github.com/robots.txt","online":false,"can_crawl_api":true,"host_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub","repositories_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories","repository_names_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repository_names","owners_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners"}},"keywords":["gp120","markov-state-model","molecular-dynamics","simulation"],"created_at":"2024-11-05T18:26:32.190Z","updated_at":"2026-02-10T01:01:25.975Z","avatar_url":"https://github.com/liyigerry.png","language":null,"funding_links":[],"categories":[],"sub_categories":[],"readme":"# Molecular dynamics simulations of HIV glycoprotein gp120\n\n### There are some research on the molecular dynamics of HIV glycoprotein gp120.\n\n| No. | Year | Journal | IF | Res | DOI |\n| :---: | :---: | :---:| :---: | :---: | :--- |\n| 1 | 2018 | RSC Advances | 3.049 | [pdf](./Neutralization/2018_RSC.pdf) [files](./Neutralization) | [10.1039/C8RA00425K](https://doi.org/10.1039/C8RA00425K) |\n| 2 | 2019 | International Journal of Molecular Sciences | 4.183 | [pdf](./Effects/2019_IJMS.pdf) [files](./Effects) | [10.3390/ijms20020260](https://doi.org/10.3390/ijms20020260) |\n| 3 | 2020 | BBA–Biomembranes | 3.79 | [pdf](./Barrier/2020_BBA.pdf) [files](./Barrier) | [10.1016/j.bbamem.2020.183217](https://doi.org/10.1016/j.bbamem.2020.183217) |\n| 4 | 2020 | Physical Chemistry Chemical Physics | 3.567 | [pdf](./Distinct/2020_PCCP.pdf) [files](./Distinct) | [10.1039/c9cp06706j](https://doi.org/10.1039/c9cp06706j) |\n\n1. Insights into molecular mechanism underlying CD4 dependency and neutralization sensitivity of HIV-1: a comparative molecular dynamics study on gp120s from isolates with different phenotypes\n2. Effects of CD4 binding on conformational dynamics, molecular motions, and thermodynamics of HIV-1 gp120\n3. CD4-binding obstacles in conformational transitions and allosteric communications of HIV gp120\n4. Molecular dynamics simulations reveal distinct differences in conformational dynamics and thermodynamics between the unliganded and CD4-bound states of HIV-1 gp120","project_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fliyigerry%2Fgp120","html_url":"https://awesome.ecosyste.ms/projects/github.com%2Fliyigerry%2Fgp120","lists_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fliyigerry%2Fgp120/lists"}