{"id":20690270,"url":"https://github.com/merck/wpgsd","last_synced_at":"2025-04-22T16:56:04.722Z","repository":{"id":147014703,"uuid":"611340338","full_name":"Merck/wpgsd","owner":"Merck","description":"Weighted parametric group sequential design","archived":false,"fork":false,"pushed_at":"2025-03-27T19:10:01.000Z","size":7236,"stargazers_count":2,"open_issues_count":2,"forks_count":2,"subscribers_count":5,"default_branch":"main","last_synced_at":"2025-04-12T12:43:33.618Z","etag":null,"topics":[],"latest_commit_sha":null,"homepage":"https://merck.github.io/wpgsd/","language":"R","has_issues":true,"has_wiki":null,"has_pages":null,"mirror_url":null,"source_name":null,"license":"gpl-3.0","status":null,"scm":"git","pull_requests_enabled":true,"icon_url":"https://github.com/Merck.png","metadata":{"files":{"readme":"README.md","changelog":"NEWS.md","contributing":null,"funding":null,"license":"LICENSE","code_of_conduct":null,"threat_model":null,"audit":null,"citation":"CITATION.cff","codeowners":null,"security":null,"support":null,"governance":null,"roadmap":null,"authors":null,"dei":null,"publiccode":null,"codemeta":null,"zenodo":null}},"created_at":"2023-03-08T16:14:22.000Z","updated_at":"2025-04-12T07:33:28.000Z","dependencies_parsed_at":null,"dependency_job_id":"88dd40f9-b9dd-4f85-aa8c-7d5c5423d6b5","html_url":"https://github.com/Merck/wpgsd","commit_stats":null,"previous_names":[],"tags_count":0,"template":false,"template_full_name":null,"repository_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/Merck%2Fwpgsd","tags_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/Merck%2Fwpgsd/tags","releases_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/Merck%2Fwpgsd/releases","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/Merck%2Fwpgsd/manifests","owner_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/Merck","download_url":"https://codeload.github.com/Merck/wpgsd/tar.gz/refs/heads/main","host":{"name":"GitHub","url":"https://github.com","kind":"github","repositories_count":250284110,"owners_count":21405288,"icon_url":"https://github.com/github.png","version":null,"created_at":"2022-05-30T11:31:42.601Z","updated_at":"2022-07-04T15:15:14.044Z","host_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub","repositories_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories","repository_names_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repository_names","owners_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners"}},"keywords":[],"created_at":"2024-11-16T23:12:28.400Z","updated_at":"2025-04-22T16:56:04.699Z","avatar_url":"https://github.com/Merck.png","language":"R","readme":"# wpgsd \u003cimg src=\"man/figures/logo.png\" align=\"right\" width=\"120\" /\u003e\n\n\u003c!-- badges: start --\u003e\n[![R-CMD-check](https://github.com/Merck/wpgsd/actions/workflows/R-CMD-check.yaml/badge.svg)](https://github.com/Merck/wpgsd/actions/workflows/R-CMD-check.yaml)\n[![Codecov test coverage](https://codecov.io/gh/Merck/wpgsd/branch/main/graph/badge.svg)](https://app.codecov.io/gh/Merck/wpgsd?branch=main)\n\u003c!-- badges: end --\u003e\n\nWeighted parametric group sequential design (WPGSD) allows one to take advantage\nof the known correlation structure in constructing efficacy bounds to control\nfamily-wise error rate (FWER) for a group sequential design. Here correlation\nmay be due to common observations in nested populations, due to common\nobservations in overlapping populations, or due to common observations\nin the control arm.\n\n## Installation\n\nThe easiest way to get wpgsd is to install from CRAN:\n\n```r\ninstall.packages(\"wpgsd\")\n```\n\nAlternatively, to use a new feature or get a bug fix,\nyou can install the development version of wpgsd from GitHub:\n\n```r\n# install.packages(\"remotes\")\nremotes::install_github(\"Merck/wpgsd\")\n```\n\n## Current limitations\n\nThere are some limitations that are currently being addressed.\nPlease use the package with caution in production environments.\n\n- The current implementation may have limitations when handling more\n  complex scenarios beyond what has been demonstrated.\n- The API is subject to potential breaking changes as it is currently\n  being reviewed and refactored.\n- Further validation is needed to ensure the reliability of the package.\n- More documentation is expected in the future releases.\n\n## References\n\nAnderson, K. M., Guo, Z., Zhao, J., \u0026 Sun, L. Z. (2022).\nA unified framework for weighted parametric group sequential design.\n_Biometrical Journal_, 64(7), 1219--1239.\n\nBibTeX entry:\n\n```\n@article{anderson2022unified,\n  title     = {A unified framework for weighted parametric group sequential design},\n  author    = {Anderson, Keaven M and Guo, Zifang and Zhao, Jing and Sun, Linda Z},\n  journal   = {Biometrical Journal},\n  volume    = {64},\n  number    = {7},\n  pages     = {1219--1239},\n  year      = {2022},\n  publisher = {Wiley Online Library}\n}\n```\n","funding_links":[],"categories":[],"sub_categories":[],"project_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fmerck%2Fwpgsd","html_url":"https://awesome.ecosyste.ms/projects/github.com%2Fmerck%2Fwpgsd","lists_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fmerck%2Fwpgsd/lists"}