{"id":29625263,"url":"https://github.com/novartis/frpipe","last_synced_at":"2025-07-21T06:07:48.740Z","repository":{"id":182050976,"uuid":"667861386","full_name":"Novartis/FRPipe","owner":"Novartis","description":"FRPipe: A 19F NMR data analysis pipeline","archived":false,"fork":false,"pushed_at":"2023-07-18T13:51:40.000Z","size":18,"stargazers_count":0,"open_issues_count":0,"forks_count":0,"subscribers_count":2,"default_branch":"main","last_synced_at":"2024-04-16T11:10:09.431Z","etag":null,"topics":[],"latest_commit_sha":null,"homepage":null,"language":"Python","has_issues":true,"has_wiki":null,"has_pages":null,"mirror_url":null,"source_name":null,"license":"mit","status":null,"scm":"git","pull_requests_enabled":true,"icon_url":"https://github.com/Novartis.png","metadata":{"files":{"readme":"README.MD","changelog":null,"contributing":null,"funding":null,"license":"LICENSE","code_of_conduct":null,"threat_model":null,"audit":null,"citation":null,"codeowners":null,"security":null,"support":null,"governance":null}},"created_at":"2023-07-18T13:17:36.000Z","updated_at":"2023-07-18T13:47:00.000Z","dependencies_parsed_at":null,"dependency_job_id":"df736432-09fe-4da4-9027-3d9fe04921ea","html_url":"https://github.com/Novartis/FRPipe","commit_stats":null,"previous_names":["novartis/frpipe"],"tags_count":0,"template":false,"template_full_name":null,"purl":"pkg:github/Novartis/FRPipe","repository_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/Novartis%2FFRPipe","tags_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/Novartis%2FFRPipe/tags","releases_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/Novartis%2FFRPipe/releases","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/Novartis%2FFRPipe/manifests","owner_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/Novartis","download_url":"https://codeload.github.com/Novartis/FRPipe/tar.gz/refs/heads/main","sbom_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/Novartis%2FFRPipe/sbom","host":{"name":"GitHub","url":"https://github.com","kind":"github","repositories_count":266248501,"owners_count":23899056,"icon_url":"https://github.com/github.png","version":null,"created_at":"2022-05-30T11:31:42.601Z","updated_at":"2022-07-04T15:15:14.044Z","host_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub","repositories_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories","repository_names_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repository_names","owners_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners"}},"keywords":[],"created_at":"2025-07-21T06:07:48.603Z","updated_at":"2025-07-21T06:07:48.726Z","avatar_url":"https://github.com/Novartis.png","language":"Python","funding_links":[],"categories":[],"sub_categories":[],"readme":"## README\n\n### about\n\nFRPipe.py is the script used to analyse 19F reporter assay data as described in \nNature Communications, Hommel et al. \"Discovery of a selective and biologically active low-molecular weight antagonist of human IL-1b\"\n\n### input data\nthe script reads preprocessed Bruker files parsing title files enriched with meta data needed for further processing\n\n### title files layout\nLigand: 123 uM LIGANDNAME (LIMS code)  \nProtein: 10 uM PROTEINNAME (Protein DB code)  \nReporter: 40 uM REPORTERNAME (LIMS code)\n\nfor the reference measurements \"Reporter only\" and \"Reporter with protein\" leave out the respective lines.\n\n### Usage\n\n```\n# simple run with a reporter KD of 120 uM.\nFRPipe.py -i /path/to/bruker/data -t /path/to/where/results/go -k 120 \n\n# -h will provide a detailed description of CLI parameters to tweak the analysis\nFRPipe.py -h \n\n```\n","project_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fnovartis%2Ffrpipe","html_url":"https://awesome.ecosyste.ms/projects/github.com%2Fnovartis%2Ffrpipe","lists_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fnovartis%2Ffrpipe/lists"}