{"id":20817688,"url":"https://github.com/splch/heterozygote-advantage","last_synced_at":"2025-03-12T05:44:22.033Z","repository":{"id":115904546,"uuid":"214493347","full_name":"splch/heterozygote-advantage","owner":"splch","description":"Simulations of populations with varying levels of natural selection to observe responses to heterozygous percentages.","archived":false,"fork":false,"pushed_at":"2024-05-30T05:15:12.000Z","size":2110,"stargazers_count":0,"open_issues_count":9,"forks_count":0,"subscribers_count":1,"default_branch":"master","last_synced_at":"2025-03-06T07:50:44.635Z","etag":null,"topics":[],"latest_commit_sha":null,"homepage":null,"language":"Jupyter Notebook","has_issues":true,"has_wiki":null,"has_pages":null,"mirror_url":null,"source_name":null,"license":null,"status":null,"scm":"git","pull_requests_enabled":true,"icon_url":"https://github.com/splch.png","metadata":{"files":{"readme":"README.md","changelog":null,"contributing":null,"funding":null,"license":null,"code_of_conduct":null,"threat_model":null,"audit":null,"citation":null,"codeowners":null,"security":null,"support":null,"governance":null,"roadmap":null,"authors":null,"dei":null,"publiccode":null,"codemeta":null}},"created_at":"2019-10-11T17:24:30.000Z","updated_at":"2022-03-03T06:35:16.000Z","dependencies_parsed_at":null,"dependency_job_id":"8daa745d-5191-4e98-8cd4-3423494136a5","html_url":"https://github.com/splch/heterozygote-advantage","commit_stats":null,"previous_names":[],"tags_count":0,"template":false,"template_full_name":null,"repository_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/splch%2Fheterozygote-advantage","tags_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/splch%2Fheterozygote-advantage/tags","releases_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/splch%2Fheterozygote-advantage/releases","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/splch%2Fheterozygote-advantage/manifests","owner_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/splch","download_url":"https://codeload.github.com/splch/heterozygote-advantage/tar.gz/refs/heads/master","host":{"name":"GitHub","url":"https://github.com","kind":"github","repositories_count":243165501,"owners_count":20246722,"icon_url":"https://github.com/github.png","version":null,"created_at":"2022-05-30T11:31:42.601Z","updated_at":"2022-07-04T15:15:14.044Z","host_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub","repositories_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories","repository_names_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repository_names","owners_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners"}},"keywords":[],"created_at":"2024-11-17T21:43:52.250Z","updated_at":"2025-03-12T05:44:22.012Z","avatar_url":"https://github.com/splch.png","language":"Jupyter Notebook","funding_links":[],"categories":[],"sub_categories":[],"readme":"# Heterozygote Advantage Simulation\nSimulations of populations with varying levels of natural selection to observe responses to heterozygous percentages.\n\n## Hypothesis\nThe rate of natural selection is directly proportional to the frequency of heterozygous genes.\n\n## Installation\n\n[![Run on Repl.it](https://replit.com/badge/github/splch/heterozygote-advantage)](https://replit.com/github/splch/heterozygote-advantage)\n\n```bash\npip install numpy scipy matplotlib pysimplegui\n```\n\n## Usage\n\u003cimg src=\"Images/GUI.png\" height=\"400px\"\u003e\n\nTo run application:\n```bash\npython hetadv.py\n```\n\nThen simply set:\n  number of genes,\n  birth rate,\n  generations,\n  and iterations\n\n*Keep in mind this program slows exponentially for more generations (especially above 20).*\n\n## Results\n\u003cimg src=\"Images/Figure_1.png\" height=\"400px\"\u003e\n\nHere we can see a strong correlation between increasing natural selection and frequency heterozygous genes.\n","project_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fsplch%2Fheterozygote-advantage","html_url":"https://awesome.ecosyste.ms/projects/github.com%2Fsplch%2Fheterozygote-advantage","lists_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fsplch%2Fheterozygote-advantage/lists"}