{"id":14068151,"url":"https://github.com/stolarczyk/BALCONY","last_synced_at":"2025-07-30T02:33:13.941Z","repository":{"id":39306645,"uuid":"121396594","full_name":"stolarczyk/BALCONY","owner":"stolarczyk","description":"R package: BALCONY (Better ALignment CONsensus analYsis)","archived":false,"fork":false,"pushed_at":"2022-06-01T09:06:57.000Z","size":3082,"stargazers_count":3,"open_issues_count":5,"forks_count":4,"subscribers_count":2,"default_branch":"master","last_synced_at":"2025-04-07T09:06:03.958Z","etag":null,"topics":["alignment","conservation","evolutionary-biology","protein","protein-tunnels"],"latest_commit_sha":null,"homepage":"","language":"R","has_issues":true,"has_wiki":null,"has_pages":null,"mirror_url":null,"source_name":null,"license":null,"status":null,"scm":"git","pull_requests_enabled":true,"icon_url":"https://github.com/stolarczyk.png","metadata":{"files":{"readme":"README.md","changelog":null,"contributing":null,"funding":null,"license":null,"code_of_conduct":null,"threat_model":null,"audit":null,"citation":null,"codeowners":null,"security":null,"support":null}},"created_at":"2018-02-13T15:05:56.000Z","updated_at":"2022-01-10T17:37:10.000Z","dependencies_parsed_at":"2022-08-21T01:10:16.750Z","dependency_job_id":null,"html_url":"https://github.com/stolarczyk/BALCONY","commit_stats":null,"previous_names":["michalstolarczyk/balcony"],"tags_count":6,"template":false,"template_full_name":null,"purl":"pkg:github/stolarczyk/BALCONY","repository_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/stolarczyk%2FBALCONY","tags_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/stolarczyk%2FBALCONY/tags","releases_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/stolarczyk%2FBALCONY/releases","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/stolarczyk%2FBALCONY/manifests","owner_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/stolarczyk","download_url":"https://codeload.github.com/stolarczyk/BALCONY/tar.gz/refs/heads/master","sbom_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/stolarczyk%2FBALCONY/sbom","host":{"name":"GitHub","url":"https://github.com","kind":"github","repositories_count":267798625,"owners_count":24145727,"icon_url":"https://github.com/github.png","version":null,"created_at":"2022-05-30T11:31:42.601Z","updated_at":"2022-07-04T15:15:14.044Z","status":"online","status_checked_at":"2025-07-30T02:00:09.044Z","response_time":70,"last_error":null,"robots_txt_status":"success","robots_txt_updated_at":"2025-07-24T06:49:26.215Z","robots_txt_url":"https://github.com/robots.txt","online":true,"can_crawl_api":true,"host_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub","repositories_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories","repository_names_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repository_names","owners_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners"}},"keywords":["alignment","conservation","evolutionary-biology","protein","protein-tunnels"],"created_at":"2024-08-13T07:05:59.040Z","updated_at":"2025-07-30T02:33:13.588Z","avatar_url":"https://github.com/stolarczyk.png","language":"R","funding_links":[],"categories":["R"],"sub_categories":[],"readme":"[![](http://cranlogs.r-pkg.org/badges/grand-total/BALCONY)](http://cranlogs.r-pkg.org/badges/grand-total/BALCONY)\n[![](http://www.r-pkg.org/badges/version-last-release/BALCONY)](http://www.r-pkg.org/badges/version-last-release/BALCONY)\n\n# BALCONY\nThis repository holds the BALCONY R package, which can be downloaded at its [CRAN](https://CRAN.R-project.org/package=BALCONY) website.\n\n**BALCONY** (Better ALignment CONsensus analYsis) is an R package that facilitates the evolutionary analysis and the\nidentification of conservation check the variablity of selected amino acids in protein\nstructure.\nOne of the unique functionalities of the BALCONY package concerns the\nanalysis of individual amino acids in primary protein structure and their neighbours\nin tertiary structure. Residues defining active site cavities, co-factor binding sites,\nselectivity filters, channels or tunnels are examples of applications for this package.\nBALCONY is flexible and versatile enough to combine and analyse evolutionary and\nstructural data in a simple and transparent manner.\n\nConservation analysis can provide insights into rational protein design. Amino\nacids favoured by evolution are attractive hot spots for mutations prediction.\nConversely, the most variable residues may also be great candidates for enzyme\nproperty enhancements since theoretically these are not fundamental for protein\nstability.\n\n## Package installation\n\n``` install.packages(\"BALCONY\") ```\n\n## Publication\n\nSee the [publication](https://doi.org/10.1186/s12859-018-2294-z) introducing the BALCONY package. \n\nAlicja Płuciennik, Michał Stolarczyk, Maria Bzówka, Agata Raczyńska, Tomasz Magdziarz, and Artur Góra. “BALCONY: An R Package for MSA and Functional Compartments of Protein Variability Analysis.” BMC Bioinformatics 19, no. 1 (August 14, 2018): 300. https://doi.org/10.1186/s12859-018-2294-z.\n","project_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fstolarczyk%2FBALCONY","html_url":"https://awesome.ecosyste.ms/projects/github.com%2Fstolarczyk%2FBALCONY","lists_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fstolarczyk%2FBALCONY/lists"}