{"id":22308556,"url":"https://github.com/sysbiochalmers/gagome-mced","last_synced_at":"2026-03-19T22:22:51.256Z","repository":{"id":96123270,"uuid":"540415226","full_name":"SysBioChalmers/GAGome-MCED","owner":"SysBioChalmers","description":null,"archived":false,"fork":false,"pushed_at":"2022-12-06T09:17:58.000Z","size":1164,"stargazers_count":1,"open_issues_count":0,"forks_count":0,"subscribers_count":3,"default_branch":"main","last_synced_at":"2025-01-30T22:51:18.537Z","etag":null,"topics":[],"latest_commit_sha":null,"homepage":null,"language":"HTML","has_issues":true,"has_wiki":null,"has_pages":null,"mirror_url":null,"source_name":null,"license":"mit","status":null,"scm":"git","pull_requests_enabled":true,"icon_url":"https://github.com/SysBioChalmers.png","metadata":{"files":{"readme":"README.md","changelog":null,"contributing":null,"funding":null,"license":"LICENSE","code_of_conduct":null,"threat_model":null,"audit":null,"citation":null,"codeowners":null,"security":null,"support":null,"governance":null,"roadmap":null,"authors":null,"dei":null,"publiccode":null,"codemeta":null}},"created_at":"2022-09-23T11:49:29.000Z","updated_at":"2023-01-16T06:56:23.000Z","dependencies_parsed_at":null,"dependency_job_id":"d2f52a36-de60-48b6-bc2c-3f007cd6886b","html_url":"https://github.com/SysBioChalmers/GAGome-MCED","commit_stats":null,"previous_names":[],"tags_count":0,"template":false,"template_full_name":null,"repository_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/SysBioChalmers%2FGAGome-MCED","tags_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/SysBioChalmers%2FGAGome-MCED/tags","releases_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/SysBioChalmers%2FGAGome-MCED/releases","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/SysBioChalmers%2FGAGome-MCED/manifests","owner_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/SysBioChalmers","download_url":"https://codeload.github.com/SysBioChalmers/GAGome-MCED/tar.gz/refs/heads/main","host":{"name":"GitHub","url":"https://github.com","kind":"github","repositories_count":245571076,"owners_count":20637276,"icon_url":"https://github.com/github.png","version":null,"created_at":"2022-05-30T11:31:42.601Z","updated_at":"2022-07-04T15:15:14.044Z","host_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub","repositories_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories","repository_names_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repository_names","owners_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners"}},"keywords":[],"created_at":"2024-12-03T20:14:22.337Z","updated_at":"2026-01-05T18:05:20.086Z","avatar_url":"https://github.com/SysBioChalmers.png","language":"HTML","funding_links":[],"categories":[],"sub_categories":[],"readme":"# `GAGome-MCED`\n\n## 🔬 Description\n\nThis repository contains code and example data sets for the publication \"Noninvasive detection of any-stage cancer using free glycosaminoglycans\".\nBoth a synthetic data set with standardized GAGome values and the code for the development of free GAGome MCED scores are available in the subfolders.\n\n## 💻 Installation and usage\n\nRun the Rmarkdown file Projpred_synth.Rmd in order to produce a model for predicting the probability of cancer using plasma and urine GAGomes as input data. A pre-knitted HTML report is also available if you are not interested in re-running the code yourself.\n\nhttps://sysbiochalmers.github.io/GAGome-MCED/projpred_synth.html\n\n## 📖 Publication\n\nThe free GAGome MCED scores are used in the publication below:\n```\nNoninvasive detection of any-stage cancer using free glycosaminoglycans\nSinisa Bratulic, Angelo Limeta, Saeed Dabestani, Helgi Birgisson, Gunilla Enblad, Karin Stålberg,\nGöran Hesselager, Michael Häggman,Martin Höglund, Oscar E Simonson, Peter Stålberg, Henrik Lindman,\nAnna Bång-Rudenstam, Matias Ekstrand, Gunjan Kumar, Ilaria Cavarretta,Massimo Alfano, Francesco Pellegrino,\nThomas Mandel-Clausen, Ali Salanti, Francesca Maccari, Fabio Galeotti, Nicola Volpi, Mads Daugaard, \nMattias Belting, Sven Lundstam, Ulrika Stierner, Jan Nyman, Bengt Bergman, Per-Henrik Edqvist, Max Levin, \nAndrea Salonia, Henrik Kjölhede, Eric Jonasch, Jens Nielsen, Francesco Gatto\nManuscript doi: 10.1073/pnas.2115328119\nManuscript link: https://www.pnas.org/doi/10.1073/pnas.2115328119\n```\n\n## 👋 Contact\n\nPlease reach out to our email with any comments, questions or concerns:\n\n[Sinisa Bratulic](mailto:bratulic@chalmers.se)\n\n[Angelo Limeta](mailto:angelol@chalmers.se)\n","project_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fsysbiochalmers%2Fgagome-mced","html_url":"https://awesome.ecosyste.ms/projects/github.com%2Fsysbiochalmers%2Fgagome-mced","lists_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fsysbiochalmers%2Fgagome-mced/lists"}