{"id":22308547,"url":"https://github.com/sysbiochalmers/human-gem","last_synced_at":"2025-04-12T13:42:56.526Z","repository":{"id":37318399,"uuid":"105752644","full_name":"SysBioChalmers/Human-GEM","owner":"SysBioChalmers","description":"The generic genome-scale metabolic model of Homo sapiens","archived":false,"fork":false,"pushed_at":"2024-06-24T23:14:29.000Z","size":327091,"stargazers_count":93,"open_issues_count":81,"forks_count":40,"subscribers_count":16,"default_branch":"main","last_synced_at":"2024-09-06T18:44:31.756Z","etag":null,"topics":["genome-scale-models","human-metabolism","standard-gem"],"latest_commit_sha":null,"homepage":"https://sysbiochalmers.github.io/Human-GEM-guide/","language":"MATLAB","has_issues":true,"has_wiki":null,"has_pages":null,"mirror_url":null,"source_name":null,"license":"cc-by-4.0","status":null,"scm":"git","pull_requests_enabled":true,"icon_url":"https://github.com/SysBioChalmers.png","metadata":{"files":{"readme":"README.md","changelog":null,"contributing":".github/CONTRIBUTING.md","funding":null,"license":"LICENSE.md","code_of_conduct":null,"threat_model":null,"audit":null,"citation":null,"codeowners":null,"security":null,"support":null,"governance":null,"roadmap":null,"authors":null,"dei":null,"publiccode":null,"codemeta":null}},"created_at":"2017-10-04T09:43:30.000Z","updated_at":"2024-09-02T22:50:55.000Z","dependencies_parsed_at":"2023-09-24T09:58:45.414Z","dependency_job_id":"77819efb-0faa-414f-a943-f4237ec3303b","html_url":"https://github.com/SysBioChalmers/Human-GEM","commit_stats":null,"previous_names":[],"tags_count":48,"template":false,"template_full_name":null,"repository_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/SysBioChalmers%2FHuman-GEM","tags_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/SysBioChalmers%2FHuman-GEM/tags","releases_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/SysBioChalmers%2FHuman-GEM/releases","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/SysBioChalmers%2FHuman-GEM/manifests","owner_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/SysBioChalmers","download_url":"https://codeload.github.com/SysBioChalmers/Human-GEM/tar.gz/refs/heads/main","host":{"name":"GitHub","url":"https://github.com","kind":"github","repositories_count":248574661,"owners_count":21127049,"icon_url":"https://github.com/github.png","version":null,"created_at":"2022-05-30T11:31:42.601Z","updated_at":"2022-07-04T15:15:14.044Z","host_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub","repositories_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories","repository_names_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repository_names","owners_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners"}},"keywords":["genome-scale-models","human-metabolism","standard-gem"],"created_at":"2024-12-03T20:14:20.706Z","updated_at":"2025-04-12T13:42:56.507Z","avatar_url":"https://github.com/SysBioChalmers.png","language":"MATLAB","funding_links":[],"categories":[],"sub_categories":[],"readme":"# Human-GEM: The generic genome-scale metabolic model of _Homo sapiens_\n\n[![Join the chat at https://gitter.im/SysBioChalmers/Human-GEM](https://badges.gitter.im/SysBioChalmers/Human-GEM.svg)](https://gitter.im/SysBioChalmers/Human-GEM?utm_source=badge\u0026utm_medium=badge\u0026utm_campaign=pr-badge\u0026utm_content=badge) [![GitHub version](https://badge.fury.io/gh/sysbiochalmers%2FHuman-GEM.svg)](https://badge.fury.io/gh/sysbiochalmers%2FHuman-GEM)\n[![DOI](https://zenodo.org/badge/105752644.svg)](https://zenodo.org/badge/latestdoi/105752644)\u003c!-- ALL-CONTRIBUTORS-BADGE:START - Do not remove or modify this section --\u003e\n[![All Contributors](https://img.shields.io/badge/all_contributors-32-success.svg)](#contributors)\n\u003c!-- ALL-CONTRIBUTORS-BADGE:END --\u003e \n\n### Brief Model Description\n\nThis repository contains the latest version of Human-GEM, a human genome-scale metabolic model. We encourage [contributions](#contributing).\n\n### Cite us:\n\nIf you use Human1 in your research, please cite:  \n\n \u003e J. L. Robinson, P. Kocabas, H. Wang, P.-E. Cholley, et al. An atlas of human metabolism. _Sci. Signal._ 13, eaaz1482 (2020). [doi:10.1126/scisignal.aaz1482](https://doi.org/10.1126/scisignal.aaz1482)\n \nStarting from Human-GEM v1.5.0, all the releases are also archived in [Zenodo](https://doi.org/10.5281/zenodo.4099692) from which specific version can be cited if used.\n\nIf you use Mouse1, Rat1, Zebrafish1, Fruitfly1, or Worm1 in your research, please cite:   \n\n  \u003e H. Wang, J. L. Robinson, P. Kocabas, J. Gustafsson, M. Anton, P.-E. Cholley, et al. Genome-scale metabolic network reconstruction of model animals as a platform for translational research. _PNAS_ 118, e2102344118 (2021). [doi.org/10.1073/pnas.2102344118](https://doi.org/10.1073/pnas.2102344118)\n\n\n\n### Model Keywords\n\n**Utilisation:** predictive simulation, multi-omics integrative analysis, model template  \n**Field:** metabolic-network reconstruction  \n**Type of Model:** reconstruction, curated  \n**Model Source:** HPA, HMR2, iHsa, iHepatocytes2322, Recon3D  \n**Omic Source:** genomics, proteomics  \n**Taxonomy:** _Homo sapiens_  \n**Metabolic System:** general metabolism  \n**Condition:** generic metabolism  \n\n\n### Model Overview\n\n|Taxonomy | Template Model | Reactions | Metabolites| Genes |\n| ------------- |:-------------:|:-------------:|:-------------:|:-----:|\n|_Homo sapiens_ |   HMR2, Recon3D, iHsa|    12971|  8455|  2887|\n\n\n## Contributing\n\nContributions are always welcome! Read more about the project's philosophy in our [wiki](https://github.com/SysBioChalmers/Human-GEM/wiki) or have a look at the [Contributing guidelines](https://github.com/SysBioChalmers/Human-GEM/blob/main/.github/CONTRIBUTING.md) before starting.\n\n\n## User Guide\n\nDetailed instructions on the installation and use of the Human-GEM model and repository can be found in the [Human-GEM user guide](https://sysbiochalmers.github.io/Human-GEM-guide/).\n\n\n## Installation\n\n### Required Software\n* A functional MATLAB installation (MATLAB 7.3 and higher).\n* The [RAVEN toolbox](https://github.com/SysBioChalmers/RAVEN).\n* The [COBRA toolbox](https://github.com/opencobra/cobratoolbox) (not necessary for most functionality).\n\n\n### Dependencies - Recommended Software\n* The libSBML MATLAB API (version [5.13.0](https://sourceforge.net/projects/sbml/files/libsbml/5.13.0/stable/MATLAB%20interface/) is recommended).\n* [Gurobi Optimizer](http://www.gurobi.com/registration/download-reg) for any simulations.\n\n\n### Installation Instructions\n* Clone the [main branch](https://github.com/SysBioChalmers/Human-GEM/tree/main) of this repository, or [download the latest release](https://github.com/SysBioChalmers/Human-GEM/releases/latest).\n* Add the directory to your MATLAB path either by using the lines below or manually (instructions [here](https://se.mathworks.com/help/matlab/ref/addpath.html?requestedDomain=www.mathworks.com)).\n```matlab\n% Replace \"/my/path/\" with the actual path to the Human-GEM folder\ncd /my/path/Human-GEM/code\n% This will add the relevant paths to the path variable in MATLAB\nHumanGEMInstaller.install\n% It is also possible to remove Human-GEM from the MATLAB path using\nHumanGEMInstaller.uninstall\n```\n\n## Model Files\n\nThe model is available as `.xml`, `.xlsx`, `.txt`, `.yml`, and `.mat` in the `model/` directory. Note that only the `.yml` version is available on branches other than `main` (e.g., `develop`), to facilitate tracking of model changes.\n\n\n## Usage\n\n#### Loading/saving the model\n\n`Human-GEM.mat` (Recommended if on `main` branch)\n* Load and save using the built-in MATLAB `load()` and `save()` functions.\n\n`Human-GEM.yml` (Recommended if on `develop` or other branches)\n* Load using the `importYaml.m` function (in `code/io/`)\n* Save using the `exportYaml.m` function (in `code/io/`)\n\n`Human-GEM.xml` (SBML format)\n* Load using the `importModel.m` function (from [RAVEN Toolbox](https://github.com/SysBioChalmers/RAVEN))\n* Save using the `exportModel.m` function (from [RAVEN Toolbox](https://github.com/SysBioChalmers/RAVEN))\n\n\n## Reaction, Metabolite, and Gene Annotations\n\nAdditional annotation information and external identifiers for Human-GEM reactions, metabolites, and genes are provided as `tsv` files in the `model/` directory (`reactions.tsv`, `metabolites.tsv`, and `genes.tsv`, respectively).  \n\nTo import/export this annotation data to/from MATLAB, use the `importTsvFile` and `exportTsvFile` functions, respectively.\n\n\n## Websites\n\n- [Metabolic Atlas](https://metabolicatlas.org/) enables visualization and exploration of Human-GEM content.\n- The [Human-GEM user guide](https://sysbiochalmers.github.io/Human-GEM-guide/) provides detailed instructions and examples for using the Human-GEM model and repository.\n\n\n## Metabolic Maps\n\nA collection of manually curated 2D metabolic maps associated with Human-GEM are stored in the [Human-maps repository](https://github.com/SysBioChalmers/Human-maps). These maps can be downloaded from the repository or explored interactively using [Metabolic Atlas](https://metabolicatlas.org/explore/map-viewer/human1).\n\n\n## Contributors\n\n\u003c!-- ALL-CONTRIBUTORS-LIST:START - Do not remove or modify this section --\u003e\n\u003c!-- prettier-ignore-start --\u003e\n\u003c!-- markdownlint-disable --\u003e\n\u003ctable\u003e\n  \u003ctbody\u003e\n    \u003ctr\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://github.com/ANiknejad\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/2682520?v=4?s=80\" width=\"80px;\" alt=\"Anne Niknejad\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003eAnne Niknejad\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3AANiknejad\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e \u003ca href=\"#content-ANiknejad\" title=\"Content\"\u003e🖋\u003c/a\u003e \u003ca href=\"#research-ANiknejad\" title=\"Research\"\u003e🔬\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://orcid.org/0000-0002-9476-4516\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/5329888?v=4?s=80\" width=\"80px;\" alt=\"Avlant\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003eAvlant\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3Aavlant\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e \u003ca href=\"#content-avlant\" title=\"Content\"\u003e🖋\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://orcid.org/0000-0001-6093-4110\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/9384349?v=4?s=80\" width=\"80px;\" alt=\"Benjamín Sánchez\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003eBenjamín Sánchez\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"#question-BenjaSanchez\" title=\"Answering Questions\"\u003e💬\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://github.com/Christoff1993\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/95428150?v=4?s=80\" width=\"80px;\" alt=\"Christoff1993\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003eChristoff1993\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3AChristoff1993\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://github.com/Christoff1993\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/95428150?v=4?s=80\" width=\"80px;\" alt=\"Christoff1993\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003eChristoff1993\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3AChristoff1993\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://orcid.org/0000-0001-9963-6057\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/18048784?v=4?s=80\" width=\"80px;\" alt=\"Daniel Weindl\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003eDaniel Weindl\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3Adweindl\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://orcid.org/0000-0002-6997-9531\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/33460176?v=4?s=80\" width=\"80px;\" alt=\"Devlin Moyer\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003eDevlin Moyer\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3ADevlin-Moyer\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e \u003ca href=\"#content-Devlin-Moyer\" title=\"Content\"\u003e🖋\u003c/a\u003e \u003ca href=\"#research-Devlin-Moyer\" title=\"Research\"\u003e🔬\u003c/a\u003e \u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/pulls?q=is%3Apr+reviewed-by%3ADevlin-Moyer\" title=\"Reviewed Pull Requests\"\u003e👀\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://orcid.org/0000-0002-3593-5792\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/7326655?v=4?s=80\" width=\"80px;\" alt=\"Eduard Kerkhoven\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003eEduard Kerkhoven\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3Aedkerk\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e \u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/commits?author=edkerk\" title=\"Code\"\u003e💻\u003c/a\u003e \u003ca href=\"#question-edkerk\" title=\"Answering Questions\"\u003e💬\u003c/a\u003e \u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/pulls?q=is%3Apr+reviewed-by%3Aedkerk\" title=\"Reviewed Pull Requests\"\u003e👀\u003c/a\u003e\u003c/td\u003e\n    \u003c/tr\u003e\n    \u003ctr\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://orcid.org/0000-0001-7475-0136\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/21077367?v=4?s=80\" width=\"80px;\" alt=\"Hao Wang\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003eHao Wang\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3AHao-Chalmers\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e \u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/commits?author=Hao-Chalmers\" title=\"Code\"\u003e💻\u003c/a\u003e \u003ca href=\"#data-Hao-Chalmers\" title=\"Data\"\u003e🔣\u003c/a\u003e \u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/commits?author=Hao-Chalmers\" title=\"Documentation\"\u003e📖\u003c/a\u003e \u003ca href=\"#ideas-Hao-Chalmers\" title=\"Ideas, Planning, \u0026 Feedback\"\u003e🤔\u003c/a\u003e \u003ca href=\"#infra-Hao-Chalmers\" title=\"Infrastructure (Hosting, Build-Tools, etc)\"\u003e🚇\u003c/a\u003e \u003ca href=\"#maintenance-Hao-Chalmers\" title=\"Maintenance\"\u003e🚧\u003c/a\u003e \u003ca href=\"#platform-Hao-Chalmers\" title=\"Packaging/porting to new platform\"\u003e📦\u003c/a\u003e \u003ca href=\"#projectManagement-Hao-Chalmers\" title=\"Project Management\"\u003e📆\u003c/a\u003e \u003ca href=\"#question-Hao-Chalmers\" title=\"Answering Questions\"\u003e💬\u003c/a\u003e \u003ca href=\"#research-Hao-Chalmers\" title=\"Research\"\u003e🔬\u003c/a\u003e \u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/pulls?q=is%3Apr+reviewed-by%3AHao-Chalmers\" title=\"Reviewed Pull Requests\"\u003e👀\u003c/a\u003e \u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/commits?author=Hao-Chalmers\" title=\"Tests\"\u003e⚠️\u003c/a\u003e \u003ca href=\"#talk-Hao-Chalmers\" title=\"Talks\"\u003e📢\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://orcid.org/0000-0002-7111-1360\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/67491919?v=4?s=80\" width=\"80px;\" alt=\"Jiahao Luo\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003eJiahao Luo\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3AJHL-452b\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e \u003ca href=\"#content-JHL-452b\" title=\"Content\"\u003e🖋\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://orcid.org/0000-0001-8567-5960\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/22366558?v=4?s=80\" width=\"80px;\" alt=\"Jonathan Robinson\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003eJonathan Robinson\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3AJonathanRob\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e \u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/commits?author=JonathanRob\" title=\"Code\"\u003e💻\u003c/a\u003e \u003ca href=\"#data-JonathanRob\" title=\"Data\"\u003e🔣\u003c/a\u003e \u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/commits?author=JonathanRob\" title=\"Documentation\"\u003e📖\u003c/a\u003e \u003ca href=\"#ideas-JonathanRob\" title=\"Ideas, Planning, \u0026 Feedback\"\u003e🤔\u003c/a\u003e \u003ca href=\"#infra-JonathanRob\" title=\"Infrastructure (Hosting, Build-Tools, etc)\"\u003e🚇\u003c/a\u003e \u003ca href=\"#maintenance-JonathanRob\" title=\"Maintenance\"\u003e🚧\u003c/a\u003e \u003ca href=\"#platform-JonathanRob\" title=\"Packaging/porting to new platform\"\u003e📦\u003c/a\u003e \u003ca href=\"#projectManagement-JonathanRob\" title=\"Project Management\"\u003e📆\u003c/a\u003e \u003ca href=\"#question-JonathanRob\" title=\"Answering Questions\"\u003e💬\u003c/a\u003e \u003ca href=\"#research-JonathanRob\" title=\"Research\"\u003e🔬\u003c/a\u003e \u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/pulls?q=is%3Apr+reviewed-by%3AJonathanRob\" title=\"Reviewed Pull Requests\"\u003e👀\u003c/a\u003e \u003ca href=\"#tutorial-JonathanRob\" title=\"Tutorials\"\u003e✅\u003c/a\u003e \u003ca href=\"#talk-JonathanRob\" title=\"Talks\"\u003e📢\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/10344158?v=4?s=80\" width=\"80px;\" alt=\"Jorge Ferreira\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003eJorge Ferreira\u003c/b\u003e\u003c/sub\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3Ajorgemlferreira\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://orcid.org/0000-0002-9966-7352\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/62765618?v=4?s=80\" width=\"80px;\" alt=\"Jose L. Cadavid\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003eJose L. Cadavid\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3ACadavidJoseL\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e \u003ca href=\"#research-CadavidJoseL\" title=\"Research\"\u003e🔬\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://github.com/juliette-cooke\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/90753730?v=4?s=80\" width=\"80px;\" alt=\"Juliette\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003eJuliette\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3Ajuliette-cooke\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e \u003ca href=\"#content-juliette-cooke\" title=\"Content\"\u003e🖋\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://orcid.org/0009-0001-2847-5425\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/119626411?v=4?s=80\" width=\"80px;\" alt=\"Justin Reimertz\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003eJustin Reimertz\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3Ajreimertz\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e \u003ca href=\"#content-jreimertz\" title=\"Content\"\u003e🖋\u003c/a\u003e \u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/pulls?q=is%3Apr+reviewed-by%3Ajreimertz\" title=\"Reviewed Pull Requests\"\u003e👀\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://orcid.org/0000-0001-9292-9463\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/45748199?v=4?s=80\" width=\"80px;\" alt=\"Marco Pagni\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003eMarco Pagni\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3Ampagni12\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e \u003ca href=\"#research-mpagni12\" title=\"Research\"\u003e🔬\u003c/a\u003e\u003c/td\u003e\n    \u003c/tr\u003e\n    \u003ctr\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://orcid.org/0000-0002-7753-9042\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/23480589?v=4?s=80\" width=\"80px;\" alt=\"Mihail Anton\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003eMihail Anton\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3Amihai-sysbio\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e \u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/commits?author=mihai-sysbio\" title=\"Code\"\u003e💻\u003c/a\u003e \u003ca href=\"#ideas-mihai-sysbio\" title=\"Ideas, Planning, \u0026 Feedback\"\u003e🤔\u003c/a\u003e \u003ca href=\"#infra-mihai-sysbio\" title=\"Infrastructure (Hosting, Build-Tools, etc)\"\u003e🚇\u003c/a\u003e \u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/pulls?q=is%3Apr+reviewed-by%3Amihai-sysbio\" title=\"Reviewed Pull Requests\"\u003e👀\u003c/a\u003e \u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/commits?author=mihai-sysbio\" title=\"Tests\"\u003e⚠️\u003c/a\u003e \u003ca href=\"#talk-mihai-sysbio\" title=\"Talks\"\u003e📢\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/26245751?v=4?s=80\" width=\"80px;\" alt=\"Pierre-Etienne Cholley\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003ePierre-Etienne Cholley\u003c/b\u003e\u003c/sub\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3Apecholleyc\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e \u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/commits?author=pecholleyc\" title=\"Code\"\u003e💻\u003c/a\u003e \u003ca href=\"#content-pecholleyc\" title=\"Content\"\u003e🖋\u003c/a\u003e \u003ca href=\"#research-pecholleyc\" title=\"Research\"\u003e🔬\u003c/a\u003e \u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/pulls?q=is%3Apr+reviewed-by%3Apecholleyc\" title=\"Reviewed Pull Requests\"\u003e👀\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/2399043?v=4?s=80\" width=\"80px;\" alt=\"Pierre-Etienne Cholley\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003ePierre-Etienne Cholley\u003c/b\u003e\u003c/sub\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3Apecholley\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://orcid.org/0000-0002-5120-9459\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/8766764?v=4?s=80\" width=\"80px;\" alt=\"PkiwiBird\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003ePkiwiBird\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3APkiwiBird\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e \u003ca href=\"#research-PkiwiBird\" title=\"Research\"\u003e🔬\u003c/a\u003e \u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/commits?author=PkiwiBird\" title=\"Code\"\u003e💻\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://orcid.org/0000-0002-6379-7024\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/38076281?v=4?s=80\" width=\"80px;\" alt=\"Pranas Grigaitis\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003ePranas Grigaitis\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3Apranasag\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e \u003ca href=\"#content-pranasag\" title=\"Content\"\u003e🖋\u003c/a\u003e \u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/commits?author=pranasag\" title=\"Code\"\u003e💻\u003c/a\u003e \u003ca href=\"#research-pranasag\" title=\"Research\"\u003e🔬\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://orcid.org/0000-0001-9788-2019\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/32029599?v=4?s=80\" width=\"80px;\" alt=\"Pınar Kocabaş\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003ePınar Kocabaş\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3Apinarkocabas\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e \u003ca href=\"#research-pinarkocabas\" title=\"Research\"\u003e🔬\u003c/a\u003e \u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/pulls?q=is%3Apr+reviewed-by%3Apinarkocabas\" title=\"Reviewed Pull Requests\"\u003e👀\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://orcid.org/0000-0003-0956-039X\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/22166601?v=4?s=80\" width=\"80px;\" alt=\"Rasool Saghaleyni\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003eRasool Saghaleyni\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"#ideas-Rasools\" title=\"Ideas, Planning, \u0026 Feedback\"\u003e🤔\u003c/a\u003e \u003ca href=\"#research-Rasools\" title=\"Research\"\u003e🔬\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://orcid.org/0000-0002-0636-4177\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/4625396?v=4?s=80\" width=\"80px;\" alt=\"Sarah Cherkaoui\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003eSarah Cherkaoui\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3Acherkaos\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e \u003ca href=\"#content-cherkaos\" title=\"Content\"\u003e🖋\u003c/a\u003e \u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/commits?author=cherkaos\" title=\"Code\"\u003e💻\u003c/a\u003e \u003ca href=\"#research-cherkaos\" title=\"Research\"\u003e🔬\u003c/a\u003e\u003c/td\u003e\n    \u003c/tr\u003e\n    \u003ctr\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://github.com/simas232\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/11994076?v=4?s=80\" width=\"80px;\" alt=\"Simonas Marcišauskas\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003eSimonas Marcišauskas\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"#question-simas232\" title=\"Answering Questions\"\u003e💬\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://github.com/TunahanCakir\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/71440332?v=4?s=80\" width=\"80px;\" alt=\"TunahanCakir\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003eTunahanCakir\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3ATunahanCakir\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://orcid.org/0000-0001-6071-9605\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/41695293?v=4?s=80\" width=\"80px;\" alt=\"Xuhang Li\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003eXuhang Li\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3AXuhangLi\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://orcid.org/0000-0001-9155-5260\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/32157802?v=4?s=80\" width=\"80px;\" alt=\"feiranl\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003efeiranl\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3Afeiranl\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e \u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/commits?author=feiranl\" title=\"Code\"\u003e💻\u003c/a\u003e \u003ca href=\"#data-feiranl\" title=\"Data\"\u003e🔣\u003c/a\u003e \u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/commits?author=feiranl\" title=\"Documentation\"\u003e📖\u003c/a\u003e \u003ca href=\"#ideas-feiranl\" title=\"Ideas, Planning, \u0026 Feedback\"\u003e🤔\u003c/a\u003e \u003ca href=\"#infra-feiranl\" title=\"Infrastructure (Hosting, Build-Tools, etc)\"\u003e🚇\u003c/a\u003e \u003ca href=\"#maintenance-feiranl\" title=\"Maintenance\"\u003e🚧\u003c/a\u003e \u003ca href=\"#platform-feiranl\" title=\"Packaging/porting to new platform\"\u003e📦\u003c/a\u003e \u003ca href=\"#projectManagement-feiranl\" title=\"Project Management\"\u003e📆\u003c/a\u003e \u003ca href=\"#research-feiranl\" title=\"Research\"\u003e🔬\u003c/a\u003e \u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/pulls?q=is%3Apr+reviewed-by%3Afeiranl\" title=\"Reviewed Pull Requests\"\u003e👀\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://orcid.org/0000-0001-5072-2659\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/32481323?v=4?s=80\" width=\"80px;\" alt=\"johan-gson\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003ejohan-gson\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3Ajohan-gson\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e \u003ca href=\"#content-johan-gson\" title=\"Content\"\u003e🖋\u003c/a\u003e \u003ca href=\"#research-johan-gson\" title=\"Research\"\u003e🔬\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://github.com/manas-kohli\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/5028979?v=4?s=80\" width=\"80px;\" alt=\"manas-kohli\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003emanas-kohli\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3Amanas-kohli\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://orcid.org/0000-0003-3947-488X\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/3072880?v=4?s=80\" width=\"80px;\" alt=\"smoretti\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003esmoretti\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3Asmoretti\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e \u003ca href=\"#research-smoretti\" title=\"Research\"\u003e🔬\u003c/a\u003e\u003c/td\u003e\n      \u003ctd align=\"center\" valign=\"top\" width=\"12.5%\"\u003e\u003ca href=\"https://orcid.org/0000-0003-2428-7061\"\u003e\u003cimg src=\"https://avatars.githubusercontent.com/u/6586371?v=4?s=80\" width=\"80px;\" alt=\"stairs\"/\u003e\u003cbr /\u003e\u003csub\u003e\u003cb\u003estairs\u003c/b\u003e\u003c/sub\u003e\u003c/a\u003e\u003cbr /\u003e\u003ca href=\"https://github.com/SysBioChalmers/Human-GEM/issues?q=author%3Astairs\" title=\"Bug reports\"\u003e🐛\u003c/a\u003e \u003ca href=\"#content-stairs\" title=\"Content\"\u003e🖋\u003c/a\u003e\u003c/td\u003e\n    \u003c/tr\u003e\n  \u003c/tbody\u003e\n\u003c/table\u003e\n\n\u003c!-- markdownlint-restore --\u003e\n\u003c!-- prettier-ignore-end --\u003e\n\n\u003c!-- ALL-CONTRIBUTORS-LIST:END --\u003e\n","project_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fsysbiochalmers%2Fhuman-gem","html_url":"https://awesome.ecosyste.ms/projects/github.com%2Fsysbiochalmers%2Fhuman-gem","lists_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fsysbiochalmers%2Fhuman-gem/lists"}