{"id":26166432,"url":"https://github.com/wolftech-innovations/alphabio","last_synced_at":"2025-07-19T06:36:32.432Z","repository":{"id":281103247,"uuid":"944217085","full_name":"WolfTech-Innovations/AlphaBIO","owner":"WolfTech-Innovations","description":"Project AlphaBIO. 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It provides a terminal-based interface (TUI) for a range of bioinformatics tasks, from basic sequence transcription and mutation to advanced sequence analysis and random sequence generation. With easy-to-use functions for both DNA and RNA sequences, AlphaBIO offers various tools for sequence analysis, mutation introduction, GC content calculation, and more.\n\n### Features:\n- **DNA/RNA Transcription**: Transcribe DNA sequences to RNA and vice versa.\n- **Mutation Introduction**: Perform point mutations, insertions, and deletions on sequences with customizable probabilities.\n- **GC Content Calculation**: Analyze the GC content percentage of a given sequence.\n- **Sequence Alignment**: Compare two sequences and highlight matching and mismatching base pairs.\n- **Reverse Complement**: Generate reverse complement sequences for DNA and RNA.\n- **Random Sequence Generation**: Create random DNA or RNA sequences with customizable GC content and length.\n- **Base Counting**: Count the occurrence of each base (A, T/U, C, G) in a sequence.\n- **TUI Interface**: Interact with the program through a terminal-based user interface for ease of use.\n\n### Installation:\n1. Clone this repository:\n   ```bash\n   git clone https://github.com/WolfTech-Innovations/AlphaBIO.git\n   ```\n2. Navigate to the project folder:\n   ```bash\n   cd AlphaBIO\n   ```\n3. Install dependencies (if any):\n   ```bash\n   pip install -r requirements.txt\n   ```\n\n### Usage:\nTo run the program:\n```bash\npython AlphaBIO.py\n```\n\nYou will be presented with an interactive menu where you can choose your sequence type (DNA or RNA) and perform various operations like mutation, transcription, reverse complement, and more.\n\n## Creating DNA that binds to and disables the target DNA:\n1. Select your sequence type (DNA or RNA).\n2. Enter your sequence.\n3. Choose operation 9.\n4. Check output.txt\n\n#### Contributions:\nIf you'd like to contribute to this project, please fork this repository, make changes, and submit a pull request!\n\n#### License:\nThis project is licensed under the GPL License.\n\n---\n","project_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fwolftech-innovations%2Falphabio","html_url":"https://awesome.ecosyste.ms/projects/github.com%2Fwolftech-innovations%2Falphabio","lists_url":"https://awesome.ecosyste.ms/api/v1/projects/github.com%2Fwolftech-innovations%2Falphabio/lists"}