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https://github.com/methodistsmab/CCCExplorer

Paper - Transcriptome analysis of individual stromal cell populations identifies stroma-tumor crosstalk in mouse lung cancer model
https://github.com/methodistsmab/CCCExplorer

Last synced: 4 months ago
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Paper - Transcriptome analysis of individual stromal cell populations identifies stroma-tumor crosstalk in mouse lung cancer model

Host: GitHub
URL: https://github.com/methodistsmab/CCCExplorer
Owner: methodistsmab
License: other
Created: 2017-09-19T15:42:53.000Z (over 6 years ago)
Default Branch: master
Last Pushed: 2024-01-26T17:39:01.000Z (5 months ago)
Last Synced: 2024-01-26T18:38:22.567Z (5 months ago)
Homepage:
Size: 27.5 MB
Stars: 5
Watchers: 0
Forks: 5
Open Issues: 3
Metadata Files:
- Readme: README.md

Lists

awesome-cell-cell-communication - CCCExplorer - [Java]- CCCExplorer is a java-based software that predicts and visualizes the gene signaling network to aid research on crosstalk identification in the tumor microenvironment. (Uncategorized / Uncategorized)

README

# CCCExplorer

CCCExplorer is a java-based software that predicts and visualizes the gene signaling network to aid research on crosstalk identification in the tumor microenvironment.
CCCExplorer integrates a computational model that we developed to uncover cell-cell communication as a direct and connected network. These cell communications range from ligand-receptor interactions to transcription factors and their target genes.

## Please cite the following paper when you use CCCExplorer.

>Transcriptome analysis of individual stromal cell populations identifies stroma-tumor crosstalk in mouse lung cancer model. H Choi, J Sheng, et al. Cell Reports, 2015. 24;10(7):1187-201

[![Alt text](https://raw.githubusercontent.com/methodistsmab/CCCExplorer/master/cccexplorer_screenshot.png)](https://www.youtube.com/watch?v=wN4vHV6hoig)

### The version 2 of CCCExplorer is under internal testing and will be comming soon.

It support multiple cell types and other new features.
![Alt text](https://raw.githubusercontent.com/methodistsmab/CCCExplorer/master/v2_1.png)
![Alt text](https://raw.githubusercontent.com/methodistsmab/CCCExplorer/master/v2_2.png)

# MacOS verison Download

>https://www.dropbox.com/s/1y1or8ougjkzu3x/CCCExplorer_MacOS.zip?dl=0

# How to use CCCExplorer

Youtube video URL:

>https://youtu.be/wN4vHV6hoig

# User Guide

Please read the guide before you run CCCExplorer

>https://github.com/methodistsmab/CCCExplorer/blob/master/CCCExplorer%20user_guide_v1.pdf

# License Agreement

>https://github.com/methodistsmab/CCCExplorer/blob/master/CCCExplorer_End_User_License_Agreement.pdf

# Grant information

>http://csbconsortium.staging.wpengine.com/?page_id=504

# Synapse Wiki

>https://www.synapse.org/#!Synapse:syn9775595/wiki/427099

# Contact

>Xiaohui Yu

>Email: [email protected]

>Jianting Sheng

>Email: [email protected]

>Wong, Stephen (PI)

>Email: [email protected]

# Houston Methodist Research Institute

[DEPARTMENT OF SYSTEMS MEDICINE & BIOENGINEERING ](https://www.houstonmethodist.org/for-health-professionals/department-programs/systems-medicine-bioengineering-smab/)