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https://github.com/seqan/seqan3

The modern C++ library for sequence analysis. Contains version 3 of the library and API docs.
https://github.com/seqan/seqan3

bioinformatics blast cpp-concepts cpp17 cpp20 fasta fastq fm-index modern samtools seqan sequence-alignment sequence-analysis

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The modern C++ library for sequence analysis. Contains version 3 of the library and API docs.

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# SeqAn3 -- the modern C++ library for sequence analysis

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[![platforms][9]][10]
[![start][11]][12]
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SeqAn3 is the new version of the popular SeqAn template library for the analysis of biological sequences.
It enables the rapid development of high-performance solutions by providing generic algorithms and data structures
for:

* sequence representation and transformation
* full-text indexing and efficient search
* sequence alignment
* input/output of common file formats

By leveraging *Modern C++* it provides unprecedented ease-of-use without sacrificing performance.

Please see the [online documentation](https://docs.seqan.de/seqan3/main_user/) for more details.

## Quick facts

* C++ header-only library: easy to integrate with your app & easy to distribute
* liberal open source license: allows integration with any app or library, requires only attribution
* very high code quality standards: >97% unit test coverage, performance regression tests, ...
* extensive API documentation & tutorials: more lines of documentation than lines of code
* aims to support any 64-bit architecture running Linux/POSIX; currently big-endian CPU architectures
like s390x are less supported

## Dependencies

| | requirement | version | comment |
|-------------------|------------------------------------------------------|----------|---------------------------------------------|
|**compiler** | [GCC](https://gcc.gnu.org) | ≥ 11 | no other compiler is currently supported! |
|**build system** | [CMake](https://cmake.org) | ≥ 3.5 | optional, but recommended |
|**required libs** | [SDSL](https://github.com/xxsds/sdsl-lite) | ≥ 3.0.3 | |
|**optional libs** | [cereal](https://github.com/USCiLab/cereal) | ≥ 1.3.1 | required for serialisation and CTD support |
| | [zlib](https://github.com/madler/zlib) | ≥ 1.2 | required for `*.gz` and `.bam` file support |
| | [bzip2](https://www.sourceware.org/bzip2) | ≥ 1.0 | required for `*.bz2` file support |

## Usage

We recommend that you use CMake to build your project:

* [Setup-Tutorial](https://docs.seqan.de/seqan3/main_user/setup.html)
* Using CMake guarantees that all optional dependencies are automatically detected and activated.

Quick-Setup without CMake:

* Clone the repository with submodules: `git clone --recurse-submodules https://github.com/seqan/seqan3.git`
* Add the following to your compiler invocation:
* the include directories of SeqAn and its dependencies
* C++20 mode
* Macros indicating the presence of zlib and bzip2 (set only if actually available in your paths!)
* The command could look like this:
```sh
g++-11 -O3 -DNDEBUG -Wall -Wextra \
-std=c++20 \
-I /path/to/seqan3/include \
-isystem /path/to/seqan3/submodules/sdsl-lite/include \
-isystem /path/to/seqan3/submodules/cereal/include \
-DSEQAN3_HAS_ZLIB=1 -DSEQAN3_HAS_BZIP2=1 \
-lz -lbz2 -pthread \
your_file.cpp
```

## Sponsorships

[![Vercel](https://raw.githubusercontent.com/seqan/seqan3/main/test/documentation/.vercel/powered-by-vercel.svg)](https://vercel.com/?utm_source=seqan&utm_campaign=oss)

Vercel is kind enough to sponsor our documentation preview-builds within our pull requests. Check them out!