https://github.com/BaderLab/FLASH-MM-analysis

Analysis scripts for benchmarking FLASH-MM and applying it to case-control and cell-type-specific comparisons in scRNA-seq datasets.
https://github.com/BaderLab/FLASH-MM-analysis

Last synced: 8 months ago
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Analysis scripts for benchmarking FLASH-MM and applying it to case-control and cell-type-specific comparisons in scRNA-seq datasets.

• Host: GitHub
• URL: https://github.com/BaderLab/FLASH-MM-analysis
• Owner: BaderLab
• License: mit
• Created: 2024-11-21T13:35:04.000Z (over 1 year ago)
• Default Branch: main
• Last Pushed: 2025-03-10T21:19:49.000Z (about 1 year ago)
• Last Synced: 2025-03-21T13:46:53.328Z (about 1 year ago)
• Language: R
• Homepage:
• Size: 130 KB
• Stars: 0
• Watchers: 3
• Forks: 0
• Open Issues: 0
• Metadata Files:
  • Readme: README.md
  • License: LICENSE

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README

          
# FLASH-MM Analysis Scripts

This repository contains scripts for data analysis and manuscript figure generation related to **FLASH-MM**, a fast and scalable algorithm for differential expression (DE) analysis in large-scale single-cell RNA-seq (scRNA-seq) datasets.

The **FLASH-MM** R package, including example case scenarios, is available at:  

[https://github.com/BaderLab/FLASHMM](https://github.com/BaderLab/FLASHMM).

- The `simu_scripts` folder includes R scripts for benchmarking FLASH-MM on simulation data.  

- The `data_analysis` folder contains scripts for case-control comparisons in the **tuberculosis immune atlas** and cell-type-specific sex comparisons in the **healthy kidney dataset**.