https://github.com/BrooksLabUCSC/FLAIR

Full-Length Alternative Isoform analysis of RNA
https://github.com/BrooksLabUCSC/FLAIR

Last synced: 2 months ago
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Full-Length Alternative Isoform analysis of RNA

• Host: GitHub
• URL: https://github.com/BrooksLabUCSC/FLAIR
• Owner: BrooksLabUCSC
• License: other
• Created: 2018-06-06T21:54:26.000Z (over 6 years ago)
• Default Branch: master
• Last Pushed: 2024-10-23T23:32:54.000Z (3 months ago)
• Last Synced: 2024-10-24T09:49:10.909Z (3 months ago)
• Language: Python
• Size: 93.1 MB
• Stars: 210
• Watchers: 14
• Forks: 71
• Open Issues: 86
• Metadata Files:
  • Readme: README.md
  • Contributing: CONTRIBUTING.md
  • License: LICENSE.txt
  • Code of conduct: CODE_OF_CONDUCT.md

Awesome Lists containing this project

• awesome-nanopore - FLAIR - [Python] - [Full-Length Alternative Isoform analysis of RNA](https://www.nature.com/articles/s41467-020-15171-6) (Software packages / Transcript discovery and quantification)

README

        
# flair

FLAIR (Full-Length Alternative Isoform analysis of RNA) for the correction, isoform definition, and alternative splicing analysis of noisy reads. FLAIR has primarily been used for nanopore cDNA, native RNA, and PacBio sequencing reads.

The complete Flair manual is available via [readthedocs](https://flair.readthedocs.io/en/latest/)

## Cite FLAIR 

If you use or discuss FLAIR, please cite the following [paper](https://www.nature.com/articles/s41467-020-15171-6):

>Tang, A.D., Soulette, C.M., van Baren, M.J. et al. Full-length transcript characterization of SF3B1 mutation in chronic lymphocytic leukemia reveals downregulation of retained introns. Nat Commun 11, 1438 (2020). https://doi.org/10.1038/s41467-020-15171-6