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https://github.com/bids-apps/HCPPipelines

A BIDS App for minimal preprocessing using the HCP Pipelines
https://github.com/bids-apps/HCPPipelines

anatomical-mri bids bidsapp functional-mri mri preprocessing

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A BIDS App for minimal preprocessing using the HCP Pipelines

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README

        

## HCP Pipelines BIDS App

This a [BIDS App](https://bids-apps.neuroimaging.io) wrapper for [HCP Pipelines](https://github.com/Washington-University/Pipelines) [v4.3.0](https://github.com/Washington-University/HCPpipelines/releases/tag/v4.3.0).
Like every BIDS App it consists of a container that includes all of the dependencies and run script that parses a [BIDS dataset](http://bids.neuroimaging.io).
BIDS Apps run on Windows, Linux, Mac as well as HPCs/clusters.

To convert DICOMs from your HCP-Style (CMRR) acquisitions to BIDS try using [heudiconv](https://github.com/nipy/heudiconv) with this [heuristic file](https://github.com/nipy/heudiconv/blob/master/heudiconv/heuristics/cmrr_heuristic.py).

### Description

The HCP Pipelines product is a set of tools (primarily, but not exclusively,
shell scripts) for processing MRI images for the [Human Connectome Project][HCP].
Among other things, these tools implement the Minimal Preprocessing Pipeline
(MPP) described in [Glasser et al. 2013][GlasserEtAl].

**This BIDS App requires that each subject has at least one T1w and one T2w scan.** Lack fMRI or dMRI scans is handled robustly. Note that while anatomicals (T1w, T2w scans) can be processed without a fieldmap, a fieldmap is mandatory for processing fMRI scans. Support for the HCP-Pipelines 'legacy' processing mode will be added in an upcoming release.

### Documentation

[Release Notes, Installation, and Usage][release-install-use]

### How to report errors
Discussion of HCP Pipeline usage and improvements can be posted to the
hcp-users discussion list. Sign up for hcp-users at
[http://humanconnectome.org/contact/#subscribe][hcp-users-subscribe].

Please open an issue if you encounter errors building this BIDS App or believe you have encountered an error specific to the BIDS App wrapper.

### Acknowledgements

Please cite [Glasser et al. 2013][GlasserEtAl] and [Smith et al. 2013][SmithEtAl].

### Usage

This App has the following command line arguments:

usage: run.py [-h]
[--participant_label PARTICIPANT_LABEL [PARTICIPANT_LABEL ...]]
[--session_label SESSION_LABEL [SESSION_LABEL ...]]
[--n_cpus N_CPUS]
[--stages {PreFreeSurfer,FreeSurfer,PostFreeSurfer,fMRIVolume,fMRISurface} [{PreFreeSurfer,FreeSurfer,PostFreeSurfer,fMRIVolume,fMRISurface} ...]]
[--coreg {MSMSulc,FS}] [--gdcoeffs GDCOEFFS] --license_key
LICENSE_KEY [-v] [--anat_unwarpdir {x,y,z,-x,-y,-z}]
[--skip_bids_validation]
bids_dir output_dir {participant}

HCP Pipelines BIDS App (T1w, T2w, fMRI)

positional arguments:
bids_dir The directory with the input dataset formatted
according to the BIDS standard.
output_dir The directory where the output files should be stored.
If you are running group level analysis this folder
should be prepopulated with the results of
theparticipant level analysis.
{participant} Level of the analysis that will be performed. Multiple
participant level analyses can be run independently
(in parallel) using the same output_dir.

optional arguments:
-h, --help show this help message and exit
--participant_label PARTICIPANT_LABEL [PARTICIPANT_LABEL ...]
The label of the participant that should be analyzed.
The label corresponds to sub- from
the BIDS spec (so it does not include "sub-"). If this
parameter is not provided all subjects should be
analyzed. Multiple participants can be specified with
a space separated list.
--session_label SESSION_LABEL [SESSION_LABEL ...]
The label of the session that should be analyzed. The
label corresponds to ses- from the BIDS
spec (so it does not include "ses-"). If this
parameter is not provided, all sessions should be
analyzed. Multiple sessions can be specified with a
space separated list.
--n_cpus N_CPUS Number of CPUs/cores available to use.
--stages {PreFreeSurfer,FreeSurfer,PostFreeSurfer,fMRIVolume,fMRISurface} [{PreFreeSurfer,FreeSurfer,PostFreeSurfer,fMRIVolume,fMRISurface} ...]
Which stages to run. Space separated list.
--coreg {MSMSulc,FS} Coregistration method to use
--gdcoeffs GDCOEFFS Path to gradients coefficients file
--license_key LICENSE_KEY
FreeSurfer license key - letters and numbers after "*"
in the email you received after registration. To
register (for free) visit
https://surfer.nmr.mgh.harvard.edu/registration.html
-v, --version show program's version number and exit
--anat_unwarpdir {x,y,z,x-,y-,z-}
Unwarp direction for 3D volumes
--skip_bids_validation, --skip-bids-validation
assume the input dataset is BIDS compliant and skip
the validation
--processing_mode {hcp,legacy,auto}, --processing-mode {hcp,legacy,auto}
Control HCP-Pipeline modehcp (HCPStyleData): require
T2w and fieldmap modalitieslegacy (LegacyStyleData):
always ignore T2w and fieldmapsauto: use T2w and/or
fieldmaps if available
--doslicetime Apply slice timing correction as part of fMRIVolume.

To run it in participant level mode (for one participant):

docker run -i --rm \
-v /Users/filo/data/ds005:/bids_dataset:ro \
-v /Users/filo/outputs:/outputs \
bids/hcppipelines \
/bids_dataset /outputs participant --participant_label 01 --license_key "XXXXXX"

### Commercial use

This BIDS App incorporates several **non-free** packages required for the HCP Pipeline, including:

- [MSM](https://github.com/ecr05/MSM_HOCR)
- [FreeSurfer](https://surfer.nmr.mgh.harvard.edu/)
- [FSL](https://fsl.fmrib.ox.ac.uk/fsl/fslwiki/Licence)
- [MATLAB Runtime](https://www.mathworks.com/products/compiler/matlab-runtime.html)

If you are considering commercial use of this App please consult the relevant licenses.

### TODO

- [ ] Add DiffusionProcessing stage
- [ ] More testing for fMRI with different resolution
- [ ] Run fMRI runs in parallel (when n_cpus present)
- [ ] Add support for TOPUP and GE fieldmaps for structural scans (please get in touch if you can provide sample data)
- [ ] Add support for GE fieldmaps for fMRI scans (please get in touch if you can provide sample data)
- [ ] Avoid copying fsaverage folder for every participant
- [ ] Add ICA FIX stage
- [ ] Add group level analysis
- [ ] Add task fMRI model fitting

[HCP]: http://www.humanconnectome.org
[GlasserEtAl]: http://www.ncbi.nlm.nih.gov/pubmed/23668970
[SmithEtAl]: http://www.ncbi.nlm.nih.gov/pubmed/23702415
[release-install-use]: hhttps://github.com/Washington-University/HCPpipelines/wiki/Installation-and-Usage-Instructions
[hcp-users-subscribe]: http://humanconnectome.org/contact/#subscribe