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https://github.com/bips-hb/srsim

An R package for simulating spontaneous reports
https://github.com/bips-hb/srsim

binary-data pharmacovigilance simulator

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An R package for simulating spontaneous reports

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# Simulating Spontaneous Reporting Systems (SRSim)

[![R-CMD-check](https://github.com/bips-hb/srsim/actions/workflows/R-CMD-check.yaml/badge.svg)](https://github.com/bips-hb/srsim/actions/workflows/R-CMD-check.yaml)

Spontaneous reporting systems are used in the field of pharmacovigilance to detect (previously unknown) associations between drugs and adverse events (AEs). This `R` package allows for simulating large spontaneous reporting data sets. See https://srs.bips.eu/ for an example on how this simulator could be used.

### Installation
To install, simply type in R

```R
devtools::install_github("bips-hb/srsim")
```

### Usage

See for usage the function descriptions, especially
```R
?SRSim::simulateSRS
```

### References

Please cite

__Adverse Drug Reaction or Innocent Bystander? A Systematic Comparison of Statistical Discovery Methods for Spontaneous Reporting Systems__\
L.J. Dijkstra, M. Garling, R. Foraita & I. Pigeot\
*Pharmacoepidemiology and Drug Safety* (2020)\
DOI:10.1002/PDS.4970

### Acknowledgements

We gratefully acknowledge the financial support from the innovation fund (“Innovationsfonds”) of the Federal Joint Committee in Germany (grant number: 01VSF16020).

### Author

Louis Dijkstra