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https://github.com/chemosim-lab/ProLIF

Interaction Fingerprints for protein-ligand complexes and more
https://github.com/chemosim-lab/ProLIF

cheminformatics docking drug-design drug-discovery mdanalysis molecular-dynamics rdkit

Last synced: 3 months ago
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Interaction Fingerprints for protein-ligand complexes and more

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README

          

ProLIF
======

.. list-table::
:widths: 12 35

* - **Documentation**
- |docs|
* - **CI**
- |tests| |codecov| |codeql|
* - **Builds**
- |conda-version| |pypi-version| |build|
* - **Dependencies**
- |mdanalysis| |rdkit|
* - **License**
- |license|

Description
-----------

ProLIF (*Protein-Ligand Interaction Fingerprints*) is a tool designed to generate
interaction fingerprints for complexes made of ligands, protein, DNA or RNA molecules
extracted from molecular dynamics trajectories, docking simulations and experimental
structures.

Documentation
-------------

The installation instructions, documentation and tutorials can be found online on
`ReadTheDocs `_.

Issues
------

If you have found a bug, please open an issue on the
`GitHub Issues `_ page.

Discussion
----------

If you have questions on how to use ProLIF, or if you want to give feedback or share
ideas and new features, please head to the
`GitHub Discussions `_ page.

Contributing
------------

If you are interested in contributing to the project, please read the
`Contribution Guidelines `_.

Citing ProLIF
-------------

Please refer to the `citation page `_
on the documentation.

License
-------

Unless otherwise noted, all files in this directory and all subdirectories are
distributed under the Apache License, Version 2.0 ::

Copyright 2017-2025 Cédric BOUYSSET

Licensed under the Apache License, Version 2.0 (the "License");
you may not use this file except in compliance with the License.
You may obtain a copy of the License at

http://www.apache.org/licenses/LICENSE-2.0

Unless required by applicable law or agreed to in writing, software
distributed under the License is distributed on an "AS IS" BASIS,
WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
See the License for the specific language governing permissions and
limitations under the License.

.. |pypi-version| image:: https://img.shields.io/pypi/v/prolif.svg
:target: https://pypi.python.org/pypi/prolif
:alt: Pypi Version

.. |conda-version| image:: https://img.shields.io/conda/vn/conda-forge/prolif.svg
:target: https://anaconda.org/conda-forge/prolif
:alt: Conda-forge version

.. |build| image:: https://github.com/chemosim-lab/ProLIF/workflows/build/badge.svg
:target: https://github.com/chemosim-lab/ProLIF/actions/workflows/build.yml
:alt: Build status

.. |tests| image:: https://github.com/chemosim-lab/ProLIF/workflows/tests/badge.svg?branch=master
:target: https://github.com/chemosim-lab/ProLIF/actions/workflows/ci.yml
:alt: Tests status

.. |codecov| image:: https://codecov.io/gh/chemosim-lab/ProLIF/branch/master/graph/badge.svg?token=2FCHV08G8A
:target: https://codecov.io/gh/chemosim-lab/ProLIF

.. |docs| image:: https://readthedocs.org/projects/prolif/badge/?version=latest
:target: https://prolif.readthedocs.io/
:alt: Documentation Status

.. |codeql| image:: https://github.com/chemosim-lab/ProLIF/workflows/CodeQL/badge.svg?branch=master
:target: https://github.com/chemosim-lab/ProLIF/actions/workflows/codeql.yml
:alt: Code quality

.. |license| image:: https://img.shields.io/pypi/l/prolif
:target: http://www.apache.org/licenses/LICENSE-2.0
:alt: License

.. |mdanalysis| image:: https://img.shields.io/badge/Powered%20by-MDAnalysis-orange.svg?logoWidth=16&logo=data:image/x-icon;base64,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
:alt: Powered by MDAnalysis
:target: https://www.mdanalysis.org

.. |rdkit| image:: https://img.shields.io/badge/Powered%20by-RDKit-3838ff.svg?logo=data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQBAMAAADt3eJSAAAABGdBTUEAALGPC/xhBQAAACBjSFJNAAB6JgAAgIQAAPoAAACA6AAAdTAAAOpgAAA6mAAAF3CculE8AAAAFVBMVEXc3NwUFP8UPP9kZP+MjP+0tP////9ZXZotAAAAAXRSTlMAQObYZgAAAAFiS0dEBmFmuH0AAAAHdElNRQfmAwsPGi+MyC9RAAAAQElEQVQI12NgQABGQUEBMENISUkRLKBsbGwEEhIyBgJFsICLC0iIUdnExcUZwnANQWfApKCK4doRBsKtQFgKAQC5Ww1JEHSEkAAAACV0RVh0ZGF0ZTpjcmVhdGUAMjAyMi0wMy0xMVQxNToyNjo0NyswMDowMDzr2J4AAAAldEVYdGRhdGU6bW9kaWZ5ADIwMjItMDMtMTFUMTU6MjY6NDcrMDA6MDBNtmAiAAAAAElFTkSuQmCC
:alt: Powered by RDKit
:target: https://www.rdkit.org/