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https://github.com/chrisarg/alien-seqalignment-parasail

Sequence Alignment tool
https://github.com/chrisarg/alien-seqalignment-parasail

bioinformatics bioinformatics-analysis bioinformatics-scripts sequence-alignment sequencing

Last synced: 5 months ago
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Sequence Alignment tool

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NAME
Alien::SeqAlignment::parasail - find, build and install the parasail
library

VERSION
version 0.05

SYNOPSIS
To execute the alignment using the command line tool:

use Alien::parasail;
system Alien::SeqAlignment::parasail->parasail_aligner, (list of options);

DESCRIPTION
This distribution provides parasail so that it can be used by other Perl
distributions that are on CPAN. The source code will be downloaded from
the parasail github repo, and if that fails it will use the location of
a fork but the author of this module. Contrary to other Alien modules,
this one will not test for a prior install of the parasail library, but
will install from source into a private share location for the use by
other modules. This strategy will avoid overwritting prior system
installs of the parasail library, and is guaranteed to use the latest
version of parasail. The build provides the static and shared libraries,
but also the CLI aligner (parasail_aligner).

METHODS
parasail_aligner
Alien::SeqAlignment::parasail->parasail_aligner

Returns the command name for running the CLI version of the parasail
aligner.

SEE ALSO
* parasail

parasail is a SIMD C (C99) library containing implementations of the
Smith-Waterman (local), Needleman-Wunsch (global), and various
semi-global pairwise sequence alignment algorithms. Here,
semi-global means insertions before the start or after the end of
either the query or target sequence are optionally not penalized.
parasail implements most known algorithms for vectorized pairwise
sequence alignment, including diagonal , blocked , striped , and
prefix scan. Therefore, parasail is a reference implementation for
these algorithms in addition to providing an implementation of the
best-performing algorithm(s) to date on today's most advanced CPUs.

parasail implements the above algorithms currently in three
variants, 1) returning the alignment score and ending locations, 2)
additionally returning alignment statistics (number of exact matches
, number of similarities, and alignment length), and 3) functions
that store a traceback for later retrieval as a SAM CIGAR string.
The three variants exist because parasail is intended to be
high-performing; calculating additional statistics or the traceback
will perform slower than simply calculating the alignment score.

* Alien

Documentation on the Alien concept itself.

* Alien::Base

The base class for this Alien.

* Alien::Build::Manual::AlienUser

Detailed manual for users of Alien classes.

* Bio::SeqAlignment

A collection of tools and libraries for aligning biological
sequences from within Perl.

AUTHOR
Christos Argyropoulos

COPYRIGHT AND LICENSE
This software is copyright (c) 2023 by Christos Argyropoulos.

This is free software; you can redistribute it and/or modify it under
the same terms as the Perl 5 programming language system itself.