https://github.com/databio/mira
R package for Methylation-based Inference of Regulatory Activity
https://github.com/databio/mira
Last synced: about 1 year ago
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R package for Methylation-based Inference of Regulatory Activity
- Host: GitHub
- URL: https://github.com/databio/mira
- Owner: databio
- Created: 2016-09-09T19:51:55.000Z (almost 10 years ago)
- Default Branch: master
- Last Pushed: 2020-04-09T19:18:46.000Z (about 6 years ago)
- Last Synced: 2025-03-26T13:11:22.360Z (over 1 year ago)
- Language: R
- Homepage: http://code.databio.org/MIRA
- Size: 6.54 MB
- Stars: 12
- Watchers: 16
- Forks: 2
- Open Issues: 2
-
Metadata Files:
- Readme: README.md
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README
# MIRA (Methylation-based Inference of Regulatory Activity)
[](https://travis-ci.org/databio/MIRA)
The MIRA package aggregates DNA methylation across the genome for instances of a genomic feature like histone ChIP peaks, transcription factor ChIP peaks, or open chromatin regions in order to give a single signature and score for that feature, which may be used to infer regulatory activity.
### Installing MIRA
MIRA may be installed from Github:
```{r}
devtools::install_github("databio/MIRA")
```
or locally after downloading/cloning the source code:
```{r}
install.packages("path/to/MIRA/directory", repos=NULL, type="source")
```
### Learning how to use MIRA
A couple of vignettes are included with the package. For an overview of the package see the "Getting Started" vignette. A more realistic example of how to use MIRA may be found in the "BiologicalApplication" vignette.