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https://github.com/deeptools/deepTools
Tools to process and analyze deep sequencing data.
https://github.com/deeptools/deepTools
bioinformatics chip-seq genomics ngs python rna-seq
Last synced: about 2 months ago
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Tools to process and analyze deep sequencing data.
- Host: GitHub
- URL: https://github.com/deeptools/deepTools
- Owner: deeptools
- License: other
- Created: 2013-07-08T12:30:28.000Z (about 11 years ago)
- Default Branch: master
- Last Pushed: 2024-04-08T10:43:01.000Z (6 months ago)
- Last Synced: 2024-04-14T10:12:48.215Z (5 months ago)
- Topics: bioinformatics, chip-seq, genomics, ngs, python, rna-seq
- Language: Python
- Size: 118 MB
- Stars: 645
- Watchers: 37
- Forks: 205
- Open Issues: 124
-
Metadata Files:
- Readme: README.md
- Changelog: CHANGES.txt
- Contributing: .github/CONTRIBUTING.md
- License: LICENSE.txt
Awesome Lists containing this project
- AwesomeGenomics - deepTools
README
# deepTools
[](http://deeptools.readthedocs.org/)
[](https://pypi.org/project/deepTools/)
[](http://bioconda.github.io/recipes/deeptools/README.html)
[](https://usegalaxy.eu/root?tool_id=deeptools_compute_matrix)
## User-friendly tools for exploring deep-sequencing data
deepTools addresses the challenge of handling the large amounts of data that are now routinely generated from DNA sequencing centers. deepTools contains useful modules to process the mapped reads data for multiple quality checks, creating **normalized coverage files** in standard bedGraph and bigWig file formats, that allow comparison between different files (for example, treatment and control). Finally, using such normalized and standardized files, deepTools can create many publication-ready **visualizations** to identify enrichments and for functional annotations of the genome.
For support or questions please post to [Biostars](http://biostars.org). For bug reports and feature requests please open an issue [on github](http://github.com/deeptools/deeptools).
### Citation:
Ramírez F, Ryan DP, Grüning B, Bhardwaj V, Kilpert F, Richter AS, Heyne S, Dündar F, Manke T. [deepTools2: a next generation web server for deep-sequencing data analysis.](https://nar.oxfordjournals.org/content/early/2016/04/12/nar.gkw257.abstract) Nucleic Acids Research. 2016 Apr 13:gkw257.
### Documentation:
Our [documentation](http://deeptools.readthedocs.org/) contains more details on the [individual tool scopes and usages](http://deeptools.readthedocs.org/en/latest/content/list_of_tools.html) and an [introduction to our deepTools Galaxy web server](http://deeptools.readthedocs.org/en/latest/content/help_galaxy_intro.html) including [step-by-step protocols](http://deeptools.readthedocs.org/en/latest/content/example_usage.html).
>Please see also the [FAQ](http://deeptools.readthedocs.org/en/latest/content/help_faq.html), which we update regularly.
Our [Gallery](http://deeptools.readthedocs.org/en/latest/content/example_gallery.html) may give you some more ideas about the scope of deepTools.
>For more specific **troubleshooting, feedback, and tool suggestions**, please post [to Biostars](http://biostars.org).
-------------------------------------------------------------------------------------------------------------------
### Installation
deepTools are available for:
* Command line usage (via pip / conda / github)
* Integration into Galaxy servers (via toolshed/API/web-browser)
There are many easy ways to install deepTools. More details can be found [here](https://deeptools.readthedocs.io/en/latest/content/installation.html).
In Brief:
**Install through pypi**
$ pip install deeptools
**Install via conda**
$ conda install -c bioconda deeptools
**Install by cloning the repository**
$ git clone https://github.com/deeptools/deepTools
$ cd deepTools
$ pip install .
deepTools can be easily integrated into [Galaxy](http://galaxyproject.org). Please see the [installation instructions in our documentation](http://deeptools.readthedocs.io/en/latest/content/installation.html#galaxy-installation) for further details.
**Note:** From version 2.3 onwards, deepTools support **python3**.
------------------------------------
This tool suite is developed by the [Bioinformatics Facility](http://www1.ie-freiburg.mpg.de/bioinformaticsfac) at the [Max Planck Institute for Immunobiology and Epigenetics, Freiburg](http://www1.ie-freiburg.mpg.de/).
[Documentation](http://deeptools.readthedocs.org/en/latest/index.html) | [deepTools Galaxy](http://deeptools.ie-freiburg.mpg.de) | [FAQ](http://deeptools.readthedocs.org/en/latest/content/help_faq.html)