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https://github.com/dermatologist/pyomop

Python package for managing OHDSI clinical data models. Includes support for LLM based plain text queries!
https://github.com/dermatologist/pyomop

cdm clinical-trials datawarehouse hacktoberfest health-data-analysis health-informatics llm ohdsi python text-to-sql

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Python package for managing OHDSI clinical data models. Includes support for LLM based plain text queries!

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# pyomop

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[![Build](https://github.com/dermatologist/pyomop/workflows/Python%20Test/badge.svg)](https://nuchange.ca)

* *Inspired by [@jbadger3's](https://github.com/jbadger3) [inspectomop](https://github.com/jbadger3/inspectomop)*

### [Documentation](https://dermatologist.github.io/pyomop/)

## UPDATE
Recently added support for **LLM based natural language queries** of OMOP CDM databases using [llama-index](examples/llm_example.py). Please install the llm extras as follows. Please be cognizant of the privacy issues with publically hosted LLMs. Any feedback will be highly appreciated. [See usage](examples/llm_example.py)!

```
pip install pyomop[llm]
```
[See usage](examples/llm_example.py).

## Description

The [OHSDI](https://www.ohdsi.org/) OMOP Common Data Model allows for the systematic analysis of healthcare observational databases. This is a python library to use the CDM v6 compliant databases using SQLAlchemy as the ORM. **pyomop** also supports converting query results to a pandas dataframe (see below) for use in machine learning pipelines. See some useful [SQL Queries here.](https://github.com/OHDSI/QueryLibrary)

## Installation (stable)

```
pip install pyomop

```

## Installation (current)

* git clone this repository and:
```
pip install -e .
```

## Usage >= 4.0.0 (Async) Example
```
from pyomop import CdmEngineFactory, CdmVocabulary, CdmVector, Cohort, Vocabulary, metadata
from sqlalchemy.future import select
import datetime
import asyncio

async def main():
cdm = CdmEngineFactory() # Creates SQLite database by default
# Postgres example (db='mysql' also supported)
# cdm = CdmEngineFactory(db='pgsql', host='', port=5432,
# user='', pw='',
# name='', schema='cdm6')

engine = cdm.engine
# Create Tables if required
await cdm.init_models(metadata)
# Create vocabulary if required
vocab = CdmVocabulary(cdm)
# vocab.create_vocab('/path/to/csv/files') # Uncomment to load vocabulary csv files

# Add a cohort
async with cdm.session() as session:
async with session.begin():
session.add(Cohort(cohort_definition_id=2, subject_id=100,
cohort_end_date=datetime.datetime.now(),
cohort_start_date=datetime.datetime.now()))
await session.commit()

# Query the cohort
stmt = select(Cohort).where(Cohort.subject_id == 100)
result = await session.execute(stmt)
for row in result.scalars():
print(row)
assert row.subject_id == 100

# Query the cohort pattern 2
cohort = await session.get(Cohort, 1)
print(cohort)
assert cohort.subject_id == 100

# Convert result to a pandas dataframe
vec = CdmVector()
vec.result = result
print(vec.df.dtypes)

result = await vec.sql_df(cdm, 'TEST') # TEST is defined in sqldict.py
for row in result:
print(row)

result = await vec.sql_df(cdm, query='SELECT * from cohort')
for row in result:
print(row)

# Close session
await session.close()
await engine.dispose()

# Run the main function
asyncio.run(main())
```

## Usage <=3.2.0

```

from pyomop import CdmEngineFactory, CdmVocabulary, CdmVector, Cohort, Vocabulary, metadata
from sqlalchemy.sql import select
import datetime

cdm = CdmEngineFactory() # Creates SQLite database by default

# Postgres example (db='mysql' also supported)
# cdm = CdmEngineFactory(db='pgsql', host='', port=5432,
# user='', pw='',
# name='', schema='cdm6')

engine = cdm.engine
# Create Tables if required
metadata.create_all(engine)
# Create vocabulary if required
vocab = CdmVocabulary(cdm)
# vocab.create_vocab('/path/to/csv/files') # Uncomment to load vocabulary csv files

# Create a Cohort (SQLAlchemy as ORM)
session = cdm.session
session.add(Cohort(cohort_definition_id=2, subject_id=100,
cohort_end_date=datetime.datetime.now(),
cohort_start_date=datetime.datetime.now()))
session.commit()

result = session.query(Cohort).all()
for row in result:
print(row)

# Convert result to a pandas dataframe
vec = CdmVector()
vec.result = result
print(vec.df.dtypes)

# Execute a query and convert it to dataframe
vec.sql_df(cdm, 'TEST') # TEST is defined in sqldict.py
print(vec.df.dtypes) # vec.df is a pandas dataframe
# OR
vec.sql_df(cdm, query='SELECT * from cohort')
print(vec.df.dtypes) # vec.df is a pandas dataframe

```

## command-line usage

```
pyomop -help
```

## Other utils

**Want to convert FHIR to pandas data frame? Try [fhiry](https://github.com/dermatologist/fhiry)**

**Use the same functions in [.NET](https://github.com/dermatologist/omopcdm-dot-net) and [Golang](https://github.com/E-Health/gocdm)!**

### Support
* Postgres
* MySQL
* SqLite
* More to follow..

## Give us a star ⭐️
If you find this project useful, give us a star. It helps others discover the project.

## Contributors

* [Bell Eapen](https://nuchange.ca) | [![Twitter Follow](https://img.shields.io/twitter/follow/beapen?style=social)](https://twitter.com/beapen)
* PRs welcome. See CONTRIBUTING.md