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https://github.com/drseb/phenopposites

Project to generate phenotype opposite_of relationships and investigate the effect on ontology-based algorithms
https://github.com/drseb/phenopposites

ontologies ontology phenomics phenotype phenotype-ontologies phenotypes phenotyping semantic-web semantics similarity-measures

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Project to generate phenotype opposite_of relationships and investigate the effect on ontology-based algorithms

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# phenopposites
Project to generate phenotype opposite_of relationships in PATO, MPO and HPO. We also investigate the effect including this reltionship in ontology-based algorithms like semantic similarity.

* lexically derived - these were obtained by looking for pairs of labels that differ according to an antonym pair (see [antonyms file](https://github.com/Phenomics/phenopposites/blob/master/antonyms/text-patterns.txt))
* logically derived - using the OWL definitions in HP/MP, and the [is opposite of](http://purl.obolibrary.org/obo/RO_0002604) relationships in PATO. See for example [increased height](https://www.ebi.ac.uk/ols/ontologies/pato/terms?iri=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FPATO_0000570).

# publication
Currently there is only a preprint version for this project. See http://biorxiv.org/content/early/2017/02/16/108977