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https://github.com/elliothershberg/interactive-mutation-browser

In silico protein surgery using ESM.
https://github.com/elliothershberg/interactive-mutation-browser

protein-language-model protein-structure

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In silico protein surgery using ESM.

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README

        

# Interactive Mutation Browser

## About

Protein Language Models (PLMs) are emerging as a category of [Foundation Model](https://en.wikipedia.org/wiki/Foundation_models) in the life sciences.
While there has been a lot of creative exploration of new ways to interaction with Large Language Models (LLMs), the application space of PLMs remains underexplored.
This project is an effort to research a new type of PLM interaction: **interactive mutation browsing**.

You can read more about the idea behind this tool and how it works [here](https://centuryofbio.substack.com/p/interactive-mutation-browser).

## Tech stack

- UI
- [Typescript](https://www.typescriptlang.org/)
- [NextJS](https://nextjs.org/)
- [Tailwind](https://tailwindcss.com/)
- Visualization
- [visx](https://airbnb.io/visx/)
- [3Dmol.js](http://3dmol.org/)
- API
- [ESM Atlas](https://esmatlas.com/)
- Infrastructure/Deployment
- [Vercel](https://vercel.com/)