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https://github.com/eolagbaju/oder

Optimising Definitions of Expressed Regions
https://github.com/eolagbaju/oder

annotation genomics rna-seq transcriptomics

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Optimising Definitions of Expressed Regions

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README

          

---
output: github_document
---

```{r, include = FALSE}
knitr::opts_chunk$set(
collapse = TRUE,
comment = "#>",
fig.path = "man/figures/README-",
out.width = "100%"
)
```

# ODER

[![Lifecycle: experimental](https://img.shields.io/badge/lifecycle-experimental-orange.svg)](https://lifecycle.r-lib.org/articles/stages.html#experimental)
[![BioC status](http://www.bioconductor.org/shields/build/release/bioc/ODER.svg)](https://bioconductor.org/checkResults/release/bioc-LATEST/ODER)
[![R-CMD-check-bioc](https://github.com/eolagbaju/ODER/workflows/R-CMD-check-bioc/badge.svg)](https://github.com/eolagbaju/ODER/actions)
[![Codecov test coverage](https://codecov.io/gh/eolagbaju/ODER/branch/master/graph/badge.svg)](https://codecov.io/gh/eolagbaju/ODER?branch=master)

The goal of `ODER` is to **O**ptimise the **D**efinition of **E**xpressed **R**egions. `ODER` is a packaged form of the method developed in the Zhang et al. 2020 publication: [Incomplete annotation has a disproportionate impact on our understanding of Mendelian and complex neurogenetic disorders](https://www.science.org/doi/10.1126/sciadv.aay8299). For a more detailed explanation of using `ODER`, please see the [vignette](https://eolagbaju.github.io/ODER/articles/ODERflow.html). For more explanation of the methodology behind `ODER`, see the mehtods section of the [original publication](https://www.science.org/doi/10.1126/sciadv.aay8299).

## Installation instructions

Get the latest stable `R` release from [CRAN](http://cran.r-project.org/). Then install `ODER` using from [Bioconductor](http://bioconductor.org/) the following code:

```{r 'install', eval = FALSE}
if (!requireNamespace("BiocManager", quietly = TRUE)) {
install.packages("BiocManager")
}

BiocManager::install("ODER")
```

And the development version from [GitHub](https://github.com/eolagbaju/ODER) with:

```{r 'install_dev', eval = FALSE}
BiocManager::install("eolagbaju/ODER")
```

## Citation

Below is the citation output from using `citation('ODER')` in R. Please
run this yourself to check for any updates on how to cite __ODER__.

```{r 'citation', eval = requireNamespace('ODER')}
message(citation("ODER"), bibtex = TRUE)
```

Please note that the `ODER` was only made possible thanks to many other R and bioinformatics software authors, which are cited either in the vignettes and/or the paper(s) describing this package.

## Code of Conduct

Please note that the `ODER` project is released with a [Contributor Code of Conduct](http://bioconductor.org/about/code-of-conduct/). By contributing to this project, you agree to abide by its terms.

## Development tools

* Continuous code testing is possible thanks to [GitHub actions](https://www.tidyverse.org/blog/2020/04/usethis-1-6-0/) through `r BiocStyle::CRANpkg('usethis')`, `r BiocStyle::CRANpkg('remotes')`, and `r BiocStyle::CRANpkg('rcmdcheck')` customized to use [Bioconductor's docker containers](https://www.bioconductor.org/help/docker/) and `r BiocStyle::Biocpkg('BiocCheck')`.
* Code coverage assessment is possible thanks to [codecov](https://codecov.io/gh) and `r BiocStyle::CRANpkg('covr')`.
* The [documentation website](http://eolagbaju.github.io/ODER) is automatically updated thanks to `r BiocStyle::CRANpkg('pkgdown')`.
* The code is styled automatically thanks to `r BiocStyle::CRANpkg('styler')`.
* The documentation is formatted thanks to `r BiocStyle::CRANpkg('devtools')` and `r BiocStyle::CRANpkg('roxygen2')`.

For more details, check the `dev` directory.

This package was developed using `r BiocStyle::Biocpkg('biocthis')`.