Ecosyste.ms: Awesome

An open API service indexing awesome lists of open source software.

Awesome Lists | Featured Topics | Projects

https://github.com/fjossinet/assemble2

Assemble2 allows you to design your RNA 2D structure interactively and to create and assemble the corresponding RNA 3D modules directly in UCSF Chimera
https://github.com/fjossinet/assemble2

bioinformatics java pdb rna rna-structure visualization

Last synced: 2 months ago
JSON representation

Assemble2 allows you to design your RNA 2D structure interactively and to create and assemble the corresponding RNA 3D modules directly in UCSF Chimera

Awesome Lists containing this project

README

        

# Assemble2: visualize, construct and study RNA architectures

Main features:

* Assemble2 allows you to visualize and edit RNA structures described in a file (CT, BPSep, FASTA, PDB) or recovered from databases (RFAM, PDB, SSTRAND).
* Assemble2 provides a panel dedicated to the dispaly and the interactive manipulation of an RNA secondary structure (2D).
* if the 2D is derived from a solved 3D, Assemble2 can load this 3D into to the viewer [UCSF Chimera](http://www.cgl.ucsf.edu/chimera/).
* Assemble2 keeps a link between the two structures, making the 2D a guide in the exploration of the solved 3D.
* this link makes also the 2D a guide for the construction of a new 3D. Each selection in the 2D can be used to query a database of 3D fragments to be assembled into a 3D model.
* Assemble2 is connected to RNA algorithms and databases made available as Web Services from a cloud in order to automate recurrent tasks of a working session:
* 2D prediction from an RNA primary sequence
* 2D annotation from an RNA tertiary structure
* 2D plot of a secondary structure
* query of 3D fragments from a 2D selection

Assemble2 has been developed with the Java language on MacOSX. It has been tested on MacOSX and Linux Ubuntu. But it should run on any operating system having a Java environment.

![Assemble2 description](media/poster-assemble2.png)

* [Documentation](https://github.com/fjossinet/assemble2/wiki)
* [Download and installation](https://github.com/fjossinet/assemble2/wiki/Download-and-installation)