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https://github.com/g3viz/g3viz

Lollipop-diagram to interactively visualize genetic mutations
https://github.com/g3viz/g3viz

bioinformatics genomics-visualization lollipop-plot variants visualize-mutation-data

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Lollipop-diagram to interactively visualize genetic mutations

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# G3viz: an R package to interactively visualize genetic mutation data using a lollipop-diagram

**Date: 2024-09-04**

[![Build Status](https://travis-ci.org/G3viz/g3viz.svg?branch=master)](https://travis-ci.org/G3viz/g3viz)
[![CRAN status](https://www.r-pkg.org/badges/version/g3viz)](https://CRAN.R-project.org/package=g3viz)
[![CRAN_monthly_download](https://cranlogs.r-pkg.org/badges/g3viz)](https://cran.r-project.org/package=g3viz)

## Live demo
- [x] [Short introduction](https://g3viz.github.io/g3viz/)
- [x] [Chart themes](https://g3viz.github.io/g3viz/chart_themes.html)

## Introduction

Intuitively and effectively visualizing genetic mutation data can help researchers to better understand genomic data and validate findings. `G3viz` is an R package which provides an easy-to-use lollipop-diagram tool. It enables users to interactively visualize detailed translational effect of genetic mutations in RStudio or a web browser, without having to know any HTML5/JavaScript technologies.

The features of `g3viz` include

- Interactive (zoom & pan, tooltip, brush selection tool, and interactive legend)
- Highlight and label positional mutations
- 8 ready-to-use chart themes
- Highly customizable with over 50 chart options and over 35 color schemes
- Save charts in PNG or high-quality SVG format
- Built-in function to retrieve protein domain information and resolve gene isoforms
- Built-in function to map genetic mutation type (a.k.a, variant classification) to mutation class

## Install `g3viz`

Install from R repository
```r
# install package
install.packages("g3viz", repos = "http://cran.us.r-project.org")
```
or install development version from github
```r
# Check if "devtools" installed
if("devtools" %in% rownames(installed.packages()) == FALSE){
install.packages("devtools")
}

# install from github
devtools::install_github("g3viz/g3viz")
```

## Reference

Guo, X., *et al*. (2020). G3viz: an R package to interactively visualize genetic mutation data using a lollipop-diagram. **Bioinformatics**, 36(3), 928-929.

## What's new

1.2.0
- [x] Updated Pfam (v37.0) (date: 2024-07-29)
- [x] Updated UniProtKB (date: 2024-07-29)
- [x] Updated `hgnc2pfam.df.rda` (date: 2024-07-29)

1.1.5
- [x] Updated getMutationsFromCbioportal (date: 2022-06-23)
- [x] Remove Dependency cgdsr; Add Dependency cBioPortalData (date: 2022-06-23)
- [x] Updated `hgnc2pfam.df.rda` (date: 2022-06-24)