https://github.com/gersteinlab/hotcommics

https://github.com/gersteinlab/hotcommics

Last synced: 2 months ago
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• Host: GitHub
• URL: https://github.com/gersteinlab/hotcommics
• Owner: gersteinlab
• Created: 2018-12-30T03:27:33.000Z (over 6 years ago)
• Default Branch: master
• Last Pushed: 2019-09-05T18:27:38.000Z (over 5 years ago)
• Last Synced: 2025-01-20T12:07:50.839Z (4 months ago)
• Language: C
• Size: 1.84 MB
• Stars: 1
• Watchers: 26
• Forks: 0
• Open Issues: 0
• Metadata Files:
  • Readme: README.txt

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README

        
# HotSpot Communities in Cancers

This integrated workflow identifies mutational hotspot communities on protein structure to predict cancer drivers.

This workflow has three main steps : 

1) Mapping of SNPs onto 3D -structure of proteins

2) Identification of communities on protein 3D-strcutures

3) Identification of hotspot communities on protein structure

Reource Datasets folder consists of hotspot communities identified by running HotCommics workflow on TCGA Pan-Cancer atlas project