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https://github.com/ihmeuw-msca/mrtool

Featured Nonlinear Mixed effects Models
https://github.com/ihmeuw-msca/mrtool

meta-regression mixed-effects nonlinear-optimization

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Featured Nonlinear Mixed effects Models

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MRTool
======

**MRTool** (Meta-Regression Tool) package is designed to solve general meta-regression problem.
The most interesting features include,

* linear and log prediction function,
* spline extension for covariates,
* direct Gaussian, Uniform and Laplace prior on fixed and random effects,
* shape constraints (monotonicity and convexity) for spline.

Advanced features include,

* spline knots ensemble,
* automatic covariate selection.

Installation
------------

Use pip to install the package

.. code-block:: shell

pip install mrtool

For more information please check the `documentation `_.