https://github.com/insightsengineering/teal.modules.bsafe

Teal modules for bsafe
https://github.com/insightsengineering/teal.modules.bsafe

clinical-trials r

Last synced: 8 months ago
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Teal modules for bsafe

• Host: GitHub
• URL: https://github.com/insightsengineering/teal.modules.bsafe
• Owner: insightsengineering
• License: other
• Created: 2023-08-04T11:18:51.000Z (almost 3 years ago)
• Default Branch: main
• Last Pushed: 2025-04-08T05:45:34.000Z (about 1 year ago)
• Last Synced: 2025-05-19T23:43:48.411Z (about 1 year ago)
• Topics: clinical-trials, r
• Language: R
• Homepage: https://insightsengineering.github.io/teal.modules.bsafe/
• Size: 10.1 MB
• Stars: 1
• Watchers: 10
• Forks: 0
• Open Issues: 0
• Metadata Files:
  • Readme: README.md
  • Changelog: NEWS.md
  • License: LICENSE

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README

          
# B-SAFE Shiny Module

[![Check 🛠](https://github.com/insightsengineering/teal.modules.bsafe/actions/workflows/check.yaml/badge.svg)](https://insightsengineering.github.io/teal.modules.bsafe/)

[![Docs 📚](https://github.com/insightsengineering/teal.modules.bsafe/actions/workflows/docs.yaml/badge.svg)](https://insightsengineering.github.io/teal.modules.bsafe/main-unit-test-report)

[![Code Coverage 📔](https://raw.githubusercontent.com/insightsengineering/teal.modules.bsafe/_xml_coverage_reports/data/main/badge.svg)](https://insightsengineering.github.io/teal.modules.bsafe/main/coverage-report/)

[![Project Status: Active – The project has reached a stable, usable state and is being actively developed.](https://www.repostatus.org/badges/latest/active.svg)](https://www.repostatus.org/#active)

[![Current Version](https://img.shields.io/github/r-package/v/insightsengineering/teal.modules.bsafe/main?color=purple\&label=package%20version)](https://github.com/insightsengineering/teal.modules.bsafe/tree/main)

## Installation

``` r

install.packages("remotes")

install.packages("teal")

remotes::install_github("https://github.com/insightsengineering/bsafe")

remotes::install_github("https://github.com/insightsengineering/teal.modules.bsafe")

```

## Usage

``` r

library(teal)

library(bsafe)

library(teal.modules.bsafe)

data <- teal.modules.bsafe::test_data

data <- teal.data::teal_data(

  bsafe_data = data,

  code = expression({

    bsafe_data <- teal.modules.bsafe::test_data

  })

) |>

  teal.data::verify()

app <- teal::init(

  data = data,

  modules = list(

    teal.modules.bsafe:::tm_bsafe(

      label = "teal.modules.bsafe",

      dataset_name = "bsafe_data"

    )

  ),

  header = "DaVinci test of bsafe as teal module"

)

shiny::shinyApp(app$ui, app$server)

```

## Further Information

B-SAFE is an R-Shiny app. The app is an innovate software tool for statistical analysis of adverse event summary data. The app can enhance the descriptive analysis for a current trial with historical information on one or more treatment arms for increased precision. It features a Bayesian Meta-Analytic Predictive (MAP) Prior approach and a robust extension, which incorporates historical information for safety analyses on adverse events into safety analyses for a new trial. The use of historical information has been used for efficacy analyses in the past and now being extended to safety analyses.

[Manual](https://github.com/insightsengineering/teal.modules.bsafe/blob/main/inst/www/manual.pdf)

[Stats Plan](https://github.com/insightsengineering/teal.modules.bsafe/blob/main/inst/www/statsplan.pdf)

[Test plan](https://github.com/insightsengineering/teal.modules.bsafe/blob/main/inst/www/test_validate_review.pdf)