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https://github.com/insightsengineering/tern

Table, Listings, and Graphs (TLG) library for common outputs used in clinical trials
https://github.com/insightsengineering/tern

clinical-trials graphs listings nest outputs r tables

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Table, Listings, and Graphs (TLG) library for common outputs used in clinical trials

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# tern

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The `tern` R package contains analysis functions to create tables and graphs used for clinical trial reporting.

The package provides a large range of functionality, such as:

Data visualizations:

- Line plots ([`g_lineplot`](https://insightsengineering.github.io/tern/latest-tag/reference/g_lineplot.html))
- Kaplan-Meier plots ([`g_km`](https://insightsengineering.github.io/tern/latest-tag/reference/g_km.html))
- Forest plots ([`g_forest`](https://insightsengineering.github.io/tern/latest-tag/reference/g_forest.html))
- STEP graphs ([`g_step`](https://insightsengineering.github.io/tern/latest-tag/reference/g_step.html))
- Individual patient plots ([`g_ipp`](https://insightsengineering.github.io/tern/latest-tag/reference/g_ipp.html))
- Waterfall plots ([`g_waterfall`](https://insightsengineering.github.io/tern/latest-tag/reference/g_waterfall.html))

Statistical model fit summaries:

- Logistic regression ([`summarize_logistic`](https://insightsengineering.github.io/tern/latest-tag/reference/summarize_logistic.html))
- Cox regression ([`summarize_coxreg`](https://insightsengineering.github.io/tern/latest-tag/reference/cox_regression.html))

Analysis tables:

- See a list of all available analyze functions [here](https://insightsengineering.github.io/tern/latest-tag/reference/analyze_functions.html)
- See a list of all available summarize functions [here](https://insightsengineering.github.io/tern/latest-tag/reference/summarize_functions.html)
- See a list of all available column-wise analysis functions [here](https://insightsengineering.github.io/tern/latest-tag/reference/analyze_colvars_functions.html)

Many of these outputs are available to be added into [`teal`](https://insightsengineering.github.io/teal/) shiny applications for interactive exploration of data. These `teal` modules are available in the [`teal.modules.clinical`](https://insightsengineering.github.io/teal.modules.clinical/) package.

See the [TLG Catalog](https://insightsengineering.github.io/tlg-catalog/) for an extensive catalog of example clinical trial tables, listings, and graphs created using `tern` functionality.

## Installation

`tern` is available on CRAN and you can install the latest released version with:

```r
install.packages("tern")
```

or you can install the latest development version directly from GitHub by running the following:

```r
# install.packages("pak")
pak::pak("insightsengineering/tern")
```

## Usage

To understand how to use this package, please refer to the [Introduction to `tern`](https://insightsengineering.github.io/tern/latest-tag/articles/tern.html) article, which provides multiple examples of code implementation.

See package vignettes `browseVignettes(package = "tern")` for usage of this package.

## Related

- [`rtables`](https://insightsengineering.github.io/rtables/) - table engine used
- [`tlg-catalog`](https://insightsengineering.github.io/tlg-catalog/) - website showcasing many examples of clinical trial tables, listings, and graphs
- [`teal.modules.clinical`](https://insightsengineering.github.io/teal.modules.clinical/) - `teal` modules for interactive data analysis

## Acknowledgment

This package is a result of a joint efforts by many developers and stakeholders. We would like to thank everyone who has contributed so far!

## Stargazers and Forkers

### Stargazers over time

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### Stargazers

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