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https://github.com/kaczmarj/meningioma

Segmentation of meningiomas in structural MR images
https://github.com/kaczmarj/meningioma

brain segmentation tumor

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Segmentation of meningiomas in structural MR images

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README

        

# Meningioma

Goals
-----
1. To automatically segment meningiomas pre- and post-surgery.
1. To assess brain's spatial recovery post-surgery.

- Data is available on [Brainbox](http://brainbox.pasteur.fr/project/meningioma)
- [Ongoing literature search](/lit_review.md)

Table of contents
-----------------
1. [Ground truth segmentation](#ground-truth-segmentation)
1. [Segmentation with slicer](#segmentation-with-slicer)
1. [ANTs brain extraction](#ants-brain-extraction)
1. [t-SNE on synthetic brain](#t-sne-on-synthetic-brain)

Ground truth segmentation
-------------------------

| case | segmented | reviewed |
|:----:|:---------:|:--------:|
| [001](http://brainbox.pasteur.fr/mri/?url=https://dl.dropbox.com/sh/71jbelduefu41xs/AADysls57HwmJT0pdbbSVI4Na/case_001_2.nii.gz) | ✔ | |
| [002](http://brainbox.pasteur.fr/mri/?url=https://dl.dropbox.com/sh/71jbelduefu41xs/AAAx8y8Mp_jh0yad1CjD2Z4Ra/case_002_2.nii.gz) | ✔ | |
| [003](http://brainbox.pasteur.fr/mri/?url=https://dl.dropbox.com/sh/71jbelduefu41xs/AABhDQJ-GQKMzHdFDGN6MrFBa/case_003_2.nii.gz) | ✔ | |

Segmentation with Slicer
------------------------

An example of semi-automatic segmentation with Slicer's Segmentation Editor module.

ANTs brain extraction
---------------------

We attempted to remove the skull with ANTs `antsBrainExtraction.sh`. Results were mixed. In some cases, the script performed well. In other cases, parts of the brain were removed, or parts of the skull (usually close to the meningioma) remained.

Above: successful brain extraction.

Above: unsuccessful brain extraction.

t-SNE on synthetic brain
------------------------

[[source](/notebooks/dim_reduction.ipynb)]

- blue == background
- green == skull
- red == brain
- cyan == tumor