https://github.com/kkmann/adoptr

Adaptive optimal two-stage designs for clinical trials made easy.
https://github.com/kkmann/adoptr

clinical-trials

Last synced: 12 months ago
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Adaptive optimal two-stage designs for clinical trials made easy.

• Host: GitHub
• URL: https://github.com/kkmann/adoptr
• Owner: kkmann
• License: other
• Created: 2018-11-29T08:20:44.000Z (over 7 years ago)
• Default Branch: master
• Last Pushed: 2024-04-11T07:52:54.000Z (over 2 years ago)
• Last Synced: 2025-08-04T12:37:05.167Z (12 months ago)
• Topics: clinical-trials
• Language: R
• Homepage: https://kkmann.github.io/adoptr/
• Size: 6.49 MB
• Stars: 8
• Watchers: 1
• Forks: 7
• Open Issues: 5
• Metadata Files:
  • Readme: README.md
  • License: LICENSE

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# adoptr 

Adaptive optimal two-stage designs for clinical trials with one or two arms. 

For details on the core theoretical background, see:

> Pilz M, Kunzmann K, Herrmann C, Rauch G, Kieser M. A variational approach to

optimal two-stage designs. *Statistics in Medicine*. 2019;38(21):4159–4171.

https://doi.org/10.1002/sim.8291

## Installation

Install the latest CRAN release via

```r

install.packages("adoptr")

```

and the development version directly from [GitHub](https://github.com/) with:

```r

devtools::install_github("kkmann/adoptr")

```

## Documentation

The documentation is hosted at https://kkmann.github.io/adoptr.

## Validation Report

We provide an extensive validation report for **adoptr** which is implemented 

using the **bookdown** package.

The sources are available at https://github.com/kkmann/adoptr-validation-report and

the last build version is hosted at https://kkmann.github.io/adoptr-validation-report.