An open API service indexing awesome lists of open source software.

https://github.com/klausweinbauer/fgutils

Utility library to query functional group properties in molecules.
https://github.com/klausweinbauer/fgutils

functional-groups molecular-graph rdkit

Last synced: 5 months ago
JSON representation

Utility library to query functional group properties in molecules.

Awesome Lists containing this project

README

          

FGUtils is a collection of utility functions for querying functional groups in
molecules from their molecular graph representation.

## Dependencies
- Python (>= 3.11)
- numpy (>= 1.26.4)
- networkx (>= 3.2.1)
- rdkit (>= 2023.09.4 optional)

Additional module dependencies.
| Module | Dependency |
| ------ | ---------- |
| fgutils.torch | [torch](https://pypi.org/project/torch/)>=2.5 |

## Installation
You can install [FGUtils](https://pypi.org/project/fgutils/) using pip.
```
pip install fgutils
```

## Getting Started
For a comprehensive description of FGUtils features read through the
[documentation](https://klausweinbauer.github.io/FGUtils/). However, querying
the functional groups for a molecule like acetylsalicylic acid is as simple as
running the following:
```
>>> from fgutils import FGQuery
>>>
>>> smiles = "O=C(C)Oc1ccccc1C(=O)O" # acetylsalicylic acid
>>> query = FGQuery()
>>> query.get(smiles)
[('ester', [0, 1, 3]), ('carboxylic_acid', [10, 11, 12])]
```

The output is a list of tuples containing the functional group name and the
corresponding atom indices.

## Acknowledgment
This project has received funding from the European Unions Horizon Europe Doctoral Network programme under the Marie-Skłodowska-Curie grant agreement No 101072930 (TACsy -- Training Alliance for Computational)