https://github.com/lhc17/HoloNet

HoloNet. Reveal the holograph of functional communication events in spatial transcriptomics. Help understand how microenvironments shaping cellular phenotypes
https://github.com/lhc17/HoloNet

bioinformatics cell-cell-communication python spatial-transcriptomics

Last synced: 3 months ago
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HoloNet. Reveal the holograph of functional communication events in spatial transcriptomics. Help understand how microenvironments shaping cellular phenotypes

• Host: GitHub
• URL: https://github.com/lhc17/HoloNet
• Owner: lhc17
• License: mit
• Created: 2022-06-03T00:18:48.000Z (over 2 years ago)
• Default Branch: main
• Last Pushed: 2023-10-18T16:11:55.000Z (about 1 year ago)
• Last Synced: 2024-07-09T15:21:33.249Z (4 months ago)
• Topics: bioinformatics, cell-cell-communication, python, spatial-transcriptomics
• Language: Python
• Homepage:
• Size: 6.47 MB
• Stars: 20
• Watchers: 1
• Forks: 3
• Open Issues: 8
• Metadata Files:
  • Readme: README.rst
  • License: LICENSE

Awesome Lists containing this project

• awesome-cell-cell-communication - HoloNet - [python]- Functional cell–cell communication events (FCEs) is mediated by ligand–receptor pairs and works directly for specific downstream response (expression of FCEs regulated target genes) in a particular microenvironment. HoloNet is designed for decoding FCEs using spatial transcriptomic data by integrating ligand–receptor pairs, cell-type spatial distribution and downstream gene expression into a deep learning model. (Uncategorized / Uncategorized)