https://github.com/mariomarroquim/hla-modeller
Script for generating 3D models of HLA molecules via Meta's ESMFold (https://esmatlas.com)
https://github.com/mariomarroquim/hla-modeller
hla-database ruby
Last synced: about 2 months ago
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Script for generating 3D models of HLA molecules via Meta's ESMFold (https://esmatlas.com)
- Host: GitHub
- URL: https://github.com/mariomarroquim/hla-modeller
- Owner: mariomarroquim
- License: mit
- Created: 2023-09-17T14:14:09.000Z (over 1 year ago)
- Default Branch: main
- Last Pushed: 2024-08-28T10:52:20.000Z (9 months ago)
- Last Synced: 2025-02-13T03:54:14.403Z (3 months ago)
- Topics: hla-database, ruby
- Language: Ruby
- Homepage:
- Size: 10.7 KB
- Stars: 1
- Watchers: 1
- Forks: 0
- Open Issues: 0
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Metadata Files:
- Readme: README.md
- License: LICENSE
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README
# HLA Modeller
This script generates 3D models of HLA molecules using Meta's ESMFold (https://esmatlas.com) with data from the latest IPD-IMGT/HLA (https://www.ebi.ac.uk/ipd/imgt/hla). For research use only. Not for diagnostic purposes.
## Instructions
Current HLA models are in the `output` folder. Of the 22,308 HLA sequences available at the latest (as of 2024-08-26) IPD-IMGT/HLA release, 14,566 had the expected length (regarding a reference mature HLA protein of the same locus) and were used to generate the models. To generate models for a newer IPD-IMGT/HLA release, run `ruby run.rb`.
## Support
You can contact me at [email protected].