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https://github.com/metapsy-project/data-depression-psiloctr

Database of psilocybin-assisted therapies for adults with depression versus control conditions.
https://github.com/metapsy-project/data-depression-psiloctr

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Database of psilocybin-assisted therapies for adults with depression versus control conditions.

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## **The `data-depression-psiloctr` dataset** 📊

[](https://doi.org/10.5281/zenodo.15714852)

The `data-depression-psiloctr` dataset is a meta-analytic research domain ([MARD](https://docs.metapsy.org/uploads/ebmental-2022-300509.pdf))
on psilocybin-assisted therapies for adults with depressive symptoms.
This MARD is part of the [Metapsy project](https://www.metapsy.org/).
The date of the last search update is provided [here](https://github.com/metapsy-project/data-depression-psiloctr/blob/master/metadata/last_search.txt).
This dataset includes **psilocybin therapies vs. control ('psilo vs ctr')** comparisons. Effect sizes are provided for outcomes at post-test and long-term follow-ups, if available.

This living database has been developed by the [**Sypres**](https://sypres.io/) (Synthesis of Psychedelic Research Studies) Collaboration. Further information on Sypres and its underlying methodology can be found in this [published article](https://sypres.io/assets/pdfs/natmh2025.pdf).

The dataset follows the [Metapsy data standard](https://docs.metapsy.org/data-preparation/format/). All included information has been independently extracted two researchers. Risk of bias ratings were conducted using the Cochrane Collaboration Risk of Bias Tool (Version 2).