Ecosyste.ms: Awesome
An open API service indexing awesome lists of open source software.
https://github.com/microsoft/biogpt
https://github.com/microsoft/biogpt
Last synced: about 1 month ago
JSON representation
- Host: GitHub
- URL: https://github.com/microsoft/biogpt
- Owner: microsoft
- License: mit
- Created: 2022-08-15T05:55:55.000Z (about 2 years ago)
- Default Branch: main
- Last Pushed: 2024-07-25T10:33:53.000Z (4 months ago)
- Last Synced: 2024-10-07T11:42:09.065Z (about 1 month ago)
- Language: Python
- Size: 30.7 MB
- Stars: 4,291
- Watchers: 69
- Forks: 450
- Open Issues: 73
-
Metadata Files:
- Readme: README.md
- License: LICENSE
- Code of conduct: CODE_OF_CONDUCT.md
- Security: SECURITY.md
- Support: SUPPORT.md
Awesome Lists containing this project
- awesome-ChatGPT-repositories - BioGPT - microsoft research has released biogpt, a large language model trained on biomedical research literature. the model achieves better-than-human performance on answering questions from the biomedical literature, as evaluated on pubmedqa. the code for the … (NLP)
README
# BioGPT
This repository contains the implementation of [BioGPT: Generative Pre-trained Transformer for Biomedical Text Generation and Mining](https://academic.oup.com/bib/advance-article/doi/10.1093/bib/bbac409/6713511?guestAccessKey=a66d9b5d-4f83-4017-bb52-405815c907b9), by Renqian Luo, Liai Sun, Yingce Xia, Tao Qin, Sheng Zhang, Hoifung Poon and Tie-Yan Liu.
# Requirements and Installation
* [PyTorch](http://pytorch.org/) version == 1.12.0
* Python version == 3.10
* fairseq version == 0.12.0:
``` bash
git clone https://github.com/pytorch/fairseq
cd fairseq
git checkout v0.12.0
pip install .
python setup.py build_ext --inplace
cd ..
```
* Moses
``` bash
git clone https://github.com/moses-smt/mosesdecoder.git
export MOSES=${PWD}/mosesdecoder
```
* fastBPE
``` bash
git clone https://github.com/glample/fastBPE.git
export FASTBPE=${PWD}/fastBPE
cd fastBPE
g++ -std=c++11 -pthread -O3 fastBPE/main.cc -IfastBPE -o fast
```
* sacremoses
``` bash
pip install sacremoses
```
* sklearn
``` bash
pip install scikit-learn
```
Remember to set the environment variables `MOSES` and `FASTBPE` to the path of Moses and fastBPE respetively, as they will be required later.
# Getting Started
## Pre-trained models
We provide our pre-trained BioGPT model checkpoints along with fine-tuned checkpoints for downstream tasks, available both through URL download as well as through the Hugging Face 🤗 Hub.
|Model|Description|URL|🤗 Hub|
|----|----|---|---|
|BioGPT|Pre-trained BioGPT model checkpoint|[link](https://msralaphilly2.blob.core.windows.net/release/BioGPT/checkpoints/Pre-trained-BioGPT.tgz?sp=r&st=2023-11-13T15:37:35Z&se=2099-12-30T23:37:35Z&spr=https&sv=2022-11-02&sr=b&sig=3CcG1TOhqJPBhkVutvVn3PtUq0vPyLBgwggUfojypfY%3D)|[link](https://huggingface.co/microsoft/biogpt)|
|BioGPT-Large|Pre-trained BioGPT-Large model checkpoint|[link](https://msralaphilly2.blob.core.windows.net/release/BioGPT/checkpoints/Pre-trained-BioGPT-Large.tgz?sp=r&st=2023-11-13T15:38:13Z&se=2099-12-30T23:38:13Z&spr=https&sv=2022-11-02&sr=b&sig=ib1SZut9wAwrsxGWtFtIZDhrnRg92dwPJmoY2lr3MTg%3D)|[link](https://huggingface.co/microsoft/biogpt-large)|
|BioGPT-QA-PubMedQA-BioGPT|Fine-tuned BioGPT for question answering task on PubMedQA|[link](https://msralaphilly2.blob.core.windows.net/release/BioGPT/checkpoints/QA-PubMedQA-BioGPT.tgz?sp=r&st=2023-11-13T15:38:43Z&se=2099-12-30T23:38:43Z&spr=https&sv=2022-11-02&sr=b&sig=A5SQae6ifsXmrsgpj4E2flhyXm4iHc%2FqO5b8HGOMyjc%3D)| |
|BioGPT-QA-PubMedQA-BioGPT-Large|Fine-tuned BioGPT-Large for question answering task on PubMedQA|[link](https://msralaphilly2.blob.core.windows.net/release/BioGPT/checkpoints/QA-PubMedQA-BioGPT-Large.tgz?sp=r&st=2023-11-13T15:39:40Z&se=2099-12-30T23:39:40Z&spr=https&sv=2022-11-02&sr=b&sig=t%2B%2FD%2BxVoIxiuyDsD0VXv%2FjSGoS0VcrdVXycYhWZoxUc%3D)||
|BioGPT-RE-BC5CDR|Fine-tuned BioGPT for relation extraction task on BC5CDR|[link](https://msralaphilly2.blob.core.windows.net/release/BioGPT/checkpoints/RE-BC5CDR-BioGPT.tgz?sp=r&st=2023-11-13T15:35:14Z&se=2099-12-30T23:35:14Z&spr=https&sv=2022-11-02&sr=b&sig=uXlLIHlVeKIbS%2BVmdzAmlNCeKdoKO2lxsSmwSi%2FH8nE%3D)| |
|BioGPT-RE-DDI|Fine-tuned BioGPT for relation extraction task on DDI|[link](https://msralaphilly2.blob.core.windows.net/release/BioGPT/checkpoints/RE-DDI-BioGPT.tgz?sp=r&st=2023-11-13T15:35:58Z&se=2099-12-30T23:35:58Z&spr=https&sv=2022-11-02&sr=b&sig=DkaQMuM%2FXAsM2p8%2BUs45ecuqhlSRF1DUYRBJNcxD6Pk%3D)| |
|BioGPT-RE-DTI|Fine-tuned BioGPT for relation extraction task on KD-DTI|[link](https://msralaphilly2.blob.core.windows.net/release/BioGPT/checkpoints/RE-DTI-BioGPT.tgz?sp=r&st=2023-11-13T15:36:23Z&se=2099-12-30T23:36:23Z&spr=https&sv=2022-11-02&sr=b&sig=bRgUZyqGuwYdM%2FVFzIv6Xa0GThkXq6bVzszmTe9c%2BKM%3D)| |
|BioGPT-DC-HoC|Fine-tuned BioGPT for document classification task on HoC|[link](https://msralaphilly2.blob.core.windows.net/release/BioGPT/checkpoints/DC-HoC-BioGPT.tgz?sp=r&st=2023-11-13T15:37:17Z&se=2099-12-30T23:37:17Z&spr=https&sv=2022-11-02&sr=b&sig=1DxroWPt%2FBppCTy7QHs842lLy8SQRcUeUwSfMzDFvl0%3D)| |
Download them and extract them to the `checkpoints` folder of this project.
For example:
``` bash
mkdir checkpoints
cd checkpoints
wget https://msralaphilly2.blob.core.windows.net/release/BioGPT/checkpoints/Pre-trained-BioGPT.tgz?sp=r&st=2023-11-13T15:37:35Z&se=2099-12-30T23:37:35Z&spr=https&sv=2022-11-02&sr=b&sig=3CcG1TOhqJPBhkVutvVn3PtUq0vPyLBgwggUfojypfY%3D
tar -zxvf Pre-trained-BioGPT.tgz
```
## Example Usage
Use pre-trained BioGPT model in your code:
```python
import torch
from fairseq.models.transformer_lm import TransformerLanguageModel
m = TransformerLanguageModel.from_pretrained(
"checkpoints/Pre-trained-BioGPT",
"checkpoint.pt",
"data",
tokenizer='moses',
bpe='fastbpe',
bpe_codes="data/bpecodes",
min_len=100,
max_len_b=1024)
m.cuda()
src_tokens = m.encode("COVID-19 is")
generate = m.generate([src_tokens], beam=5)[0]
output = m.decode(generate[0]["tokens"])
print(output)
```
Use fine-tuned BioGPT model on KD-DTI for drug-target-interaction in your code:
```python
import torch
from src.transformer_lm_prompt import TransformerLanguageModelPrompt
m = TransformerLanguageModelPrompt.from_pretrained(
"checkpoints/RE-DTI-BioGPT",
"checkpoint_avg.pt",
"data/KD-DTI/relis-bin",
tokenizer='moses',
bpe='fastbpe',
bpe_codes="data/bpecodes",
max_len_b=1024,
beam=1)
m.cuda()
src_text="" # input text, e.g., a PubMed abstract
src_tokens = m.encode(src_text)
generate = m.generate([src_tokens], beam=args.beam)[0]
output = m.decode(generate[0]["tokens"])
print(output)
```
For more downstream tasks, please see below.
## Downstream tasks
See corresponding folder in [examples](examples):
### [Relation Extraction on BC5CDR](examples/RE-BC5CDR)
### [Relation Extraction on KD-DTI](examples/RE-DTI/)
### [Relation Extraction on DDI](examples/RE-DDI)
### [Document Classification on HoC](examples/DC-HoC/)
### [Question Answering on PubMedQA](examples/QA-PubMedQA/)
### [Text Generation](examples/text-generation/)
## Hugging Face 🤗 Usage
BioGPT has also been integrated into the Hugging Face `transformers` library, and model checkpoints are available on the Hugging Face Hub.
You can use this model directly with a pipeline for text generation. Since the generation relies on some randomness, we set a seed for reproducibility:
```python
from transformers import pipeline, set_seed
from transformers import BioGptTokenizer, BioGptForCausalLM
model = BioGptForCausalLM.from_pretrained("microsoft/biogpt")
tokenizer = BioGptTokenizer.from_pretrained("microsoft/biogpt")
generator = pipeline('text-generation', model=model, tokenizer=tokenizer)
set_seed(42)
generator("COVID-19 is", max_length=20, num_return_sequences=5, do_sample=True)
```
Here is how to use this model to get the features of a given text in PyTorch:
```python
from transformers import BioGptTokenizer, BioGptForCausalLM
tokenizer = BioGptTokenizer.from_pretrained("microsoft/biogpt")
model = BioGptForCausalLM.from_pretrained("microsoft/biogpt")
text = "Replace me by any text you'd like."
encoded_input = tokenizer(text, return_tensors='pt')
output = model(**encoded_input)
```
Beam-search decoding:
```python
import torch
from transformers import BioGptTokenizer, BioGptForCausalLM, set_seed
tokenizer = BioGptTokenizer.from_pretrained("microsoft/biogpt")
model = BioGptForCausalLM.from_pretrained("microsoft/biogpt")
sentence = "COVID-19 is"
inputs = tokenizer(sentence, return_tensors="pt")
set_seed(42)
with torch.no_grad():
beam_output = model.generate(**inputs,
min_length=100,
max_length=1024,
num_beams=5,
early_stopping=True
)
tokenizer.decode(beam_output[0], skip_special_tokens=True)
```
For more information, please see the [documentation](https://huggingface.co/docs/transformers/main/en/model_doc/biogpt) on the Hugging Face website.
## Demos
Check out these demos on Hugging Face Spaces:
* [Text Generation with BioGPT-Large](https://huggingface.co/spaces/katielink/biogpt-large-demo)
* [Question Answering with BioGPT-Large-PubMedQA](https://huggingface.co/spaces/katielink/biogpt-qa-demo)
# License
BioGPT is MIT-licensed.
The license applies to the pre-trained models as well.
# Contributing
This project welcomes contributions and suggestions. Most contributions require you to agree to a
Contributor License Agreement (CLA) declaring that you have the right to, and actually do, grant us
the rights to use your contribution. For details, visit https://cla.opensource.microsoft.com.
When you submit a pull request, a CLA bot will automatically determine whether you need to provide
a CLA and decorate the PR appropriately (e.g., status check, comment). Simply follow the instructions
provided by the bot. You will only need to do this once across all repos using our CLA.
This project has adopted the [Microsoft Open Source Code of Conduct](https://opensource.microsoft.com/codeofconduct/).
For more information see the [Code of Conduct FAQ](https://opensource.microsoft.com/codeofconduct/faq/) or
contact [[email protected]](mailto:[email protected]) with any additional questions or comments.
# Trademarks
This project may contain trademarks or logos for projects, products, or services. Authorized use of Microsoft
trademarks or logos is subject to and must follow
[Microsoft's Trademark & Brand Guidelines](https://www.microsoft.com/en-us/legal/intellectualproperty/trademarks/usage/general).
Use of Microsoft trademarks or logos in modified versions of this project must not cause confusion or imply Microsoft sponsorship.
Any use of third-party trademarks or logos are subject to those third-party's policies.