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https://github.com/mne-tools/mne-denoise

mne-denoise provides narrow-band artefact removal tailored to MNE-Python workflows. It wraps harmonic regression techniques to suppress power-line noise and other oscillatory contaminants while preserving signal rank and interpretability.
https://github.com/mne-tools/mne-denoise

bci brain-computer-interface datacleaning dss eeg neuroscience noiseremoval python

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mne-denoise provides narrow-band artefact removal tailored to MNE-Python workflows. It wraps harmonic regression techniques to suppress power-line noise and other oscillatory contaminants while preserving signal rank and interpretability.

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# mne-denoise

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**Advanced denoising algorithms for M/EEG data in MNE-Python.**

`mne-denoise` provides powerful signal denoising techniques for the MNE-Python ecosystem, including **Denoising Source Separation (DSS)** and **ZapLine** algorithms. These methods excel at extracting signals of interest by exploiting data structure rather than just variance.

## Features

### DSS Module

- **Linear DSS**: Extract components based on reproducibility across trials or characteristic frequencies
- **Iterative DSS**: Powerful nonlinear separation for complex non-Gaussian sources
- **20+ Pluggable Denoisers**: Spectral, temporal, periodic, and ICA-style bias functions
- **Specialized Variants**: TSR, SSVEP enhancement, narrowband oscillation extraction

### ZapLine Module

- **ZapLine**: Efficient removal of power line noise (50/60 Hz) and harmonics
- **ZapLine-plus**: Fully adaptive mode with automatic frequency detection
- **Per-chunk Processing**: Handles non-stationary noise characteristics
- **Quality Assurance**: Built-in spectral checks to prevent over-cleaning

### Integration

- **MNE-Python**: Works directly with `Raw`, `Epochs`, and `Evoked` objects or `numpy` arrays.
- **Scikit-Learn API**: Standard `fit()`, `transform()`, `fit_transform()` interface
- **Visualization**: Built-in plotting for components and cleaning results

## Installation

### From PyPI (recommended)

```bash
pip install mne-denoise
```

### From source (development)

```bash
git clone https://github.com/mne-tools/mne-denoise.git
cd mne-denoise
pip install -e ".[dev]"
```

## Quick Start

### DSS: Enhancing Evoked Responses

DSS finds spatial filters that maximize the ratio of reproducible (evoked) to total power:

```python
import mne
from mne_denoise.dss import DSS, AverageBias

# Load your epoched data
epochs = mne.read_epochs("sample-epo.fif")

# Create DSS with trial-average bias
dss = DSS(bias=AverageBias(), n_components=5)
dss.fit(epochs)

# Option 1: Extract source time courses
sources = dss.transform(epochs)

# Option 2: Reconstruct denoised sensor data
cleaned_epochs = dss.transform(epochs, return_type="epochs")
```

### DSS: Extracting Oscillations

Isolate specific frequency bands (e.g., alpha rhythm):

```python
from mne_denoise.dss import DSS, BandpassBias

# Create bandpass bias for alpha (8-12 Hz)
bias = BandpassBias(sfreq=epochs.info["sfreq"], freq=10, bandwidth=4)

dss = DSS(bias=bias, n_components=3)
alpha_sources = dss.fit_transform(epochs)
```

### ZapLine: Removing Line Noise

Remove 50/60 Hz power line artifacts:

```python
import mne
from mne_denoise.zapline import ZapLine

# Load continuous data
raw = mne.io.read_raw_fif("sample-raw.fif", preload=True)

# Standard mode: specify line frequency
zapline = ZapLine(sfreq=raw.info["sfreq"], line_freq=50.0)
cleaned_data = zapline.fit_transform(raw)

# Adaptive mode: automatic detection and per-chunk processing
zapline_plus = ZapLine(
sfreq=raw.info["sfreq"],
line_freq=None, # Auto-detect
adaptive=True,
)
cleaned = zapline_plus.fit_transform(raw)
print(f"Detected line frequency: {zapline_plus.detected_freq_} Hz")
```

## Documentation

Full documentation is available at **[mne.tools/mne-denoise](https://mne.tools/mne-denoise/)**.

- [Getting Started Guide](https://mne.tools/mne-denoise/getting-started.html)
- [API Reference](https://mne.tools/mne-denoise/api.html)
- [Example Gallery](https://mne.tools/mne-denoise/auto_examples/index.html)

## πŸ—οΈ Architecture

```
mne_denoise/
β”œβ”€β”€ dss/ # Denoising Source Separation
β”‚ β”œβ”€β”€ linear.py # Core DSS algorithm, DSS estimator
β”‚ β”œβ”€β”€ nonlinear.py # Iterative DSS, IterativeDSS estimator
β”‚ β”œβ”€β”€ denoisers/ # 20+ pluggable bias functions
β”‚ β”‚ β”œβ”€β”€ spectral.py # BandpassBias, LineNoiseBias
β”‚ β”‚ β”œβ”€β”€ temporal.py # TimeShiftBias, SmoothingBias
β”‚ β”‚ β”œβ”€β”€ periodic.py # CombFilterBias, PeakFilterBias
β”‚ β”‚ └── ...
β”‚ └── variants/ # Pre-built applications
β”‚ β”œβ”€β”€ tsr.py # Time-Shift Repeatability
β”‚ β”œβ”€β”€ ssvep.py # SSVEP enhancement
β”‚ └── narrowband.py # Oscillation extraction
β”œβ”€β”€ zapline/ # Line noise removal
β”‚ β”œβ”€β”€ core.py # ZapLine estimator
β”‚ └── adaptive.py # ZapLine-plus utilities
└── viz/ # Visualization tools
```

## Testing

```bash
# Run tests
pytest

# With coverage
pytest --cov=mne_denoise --cov-report=html
```

## Contributing

We welcome contributions! Please see [CONTRIBUTING.md](CONTRIBUTING.md) for guidelines.

```bash
# Development setup
git clone https://github.com//mne-denoise.git
cd mne-denoise
pip install -e ".[dev,docs]"
pre-commit install
```

## References

### DSS

> SΓ€relΓ€, J., & Valpola, H. (2005). Denoising source separation. _Journal of Machine Learning Research_, 6, 233-272.

> de CheveignΓ©, A., & Simon, J. Z. (2008). Denoising based on spatial filtering. _Journal of Neuroscience Methods_, 171(2), 331-339.

### ZapLine

> de CheveignΓ©, A. (2020). ZapLine: A simple and effective method to remove power line artifacts. _NeuroImage_, 207, 116356.

> Klug, M., & Kloosterman, N. A. (2022). Zapline-plus: A completely automatic and highly effective method for removing power line noise. _Human Brain Mapping_, 43(9), 2743-2758.

## License

BSD 3-Clause License. See [LICENSE](LICENSE) for details.