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https://github.com/nki-ai/dlup

Dlup are the Deep Learning Utilities for Pathology developed at the Netherlands Cancer Institute
https://github.com/nki-ai/dlup

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Dlup are the Deep Learning Utilities for Pathology developed at the Netherlands Cancer Institute

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# Deep Learning Utilities for Pathology

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Dlup offers a set of utilities to ease the process of running Deep Learning algorithms on
Whole Slide Images.

## Features

- Read whole-slide images at any arbitrary resolution by seamlessly interpolating between the pyramidal levels
- Supports multiple backends, including [OpenSlide](https://openslide.org/) and [fastslide](https://github.com/NKI-AI/fastslide.git), with the possibility to add custom backends
- Dataset classes to handle whole-slide images in a tile-by-tile manner compatible with pytorch
- Annotation classes which can load GeoJSON, [V7 Darwin](https://www.v7labs.com/), [HALO](https://indicalab.com/halo/) and [ASAP](https://computationalpathologygroup.github.io/ASAP/) formats and read parts of it (e.g. a tile)
- Transforms to handle annotations per tile, resulting, together with the dataset classes a dataset consisting of tiles of whole-slide images with corresponding masks as targets, readily useable with a pytorch dataloader
- Command-line utilities to report on the metadata of WSIs, and convert masks to polygons

Check the [full documentation](https://docs.aiforoncology.nl/dlup) for more details on how to use dlup.

## Quickstart

The package can be installed using `python -m pip install dlup`. Preferably use `uv` and `uv pip install dlup`.

If you wish to install from source, you can run `uv pip install .` You will need the boost package to build from source.

## Used by

- [ahcore](https://github.com/NKI-AI/ahcore.git): a pytorch lightning based-library for computational pathology

## Citing DLUP

If you use DLUP in your research, please use the following BiBTeX entry:

```
@software{dlup,
author = {Teuwen, J., Romor, L., Pai, A., Schirris, Y., Marcus, E.},
month = {8},
title = {{DLUP: Deep Learning Utilities for Pathology}},
url = {https://github.com/NKI-AI/dlup},
version = {0.8.0},
year = {2024}
}
```

or the following plain bibliography:

```
Teuwen, J., Romor, L., Pai, A., Schirris, Y., Marcus E. (2024). DLUP: Deep Learning Utilities for Pathology (Version 0.8.0) [Computer software]. https://github.com/NKI-AI/dlup
```

## Contributors

In alphabetic order:

| [
Ajey Pai Karkala](https://github.com/AjeyPaiK) | [
Eric Marcus](https://github.com/EricMarcus-ai) | [
Jonas Teuwen](https://github.com/jonasteuwen) | [
Leonardo Romor](https://github.com/lromor) | [
Rolf Harkes](https://github.com/rharkes) | [
Yoni Schirris](https://github.com/YoniSchirris) |
| :----------------------------------------------------------------------------------------------------------------------------------------------------------: | :---------------------------------------------------------------------------------------------------------------------------------------------------------------: | :------------------------------------------------------------------------------------------------------------------------------------------------------------: | :----------------------------------------------------------------------------------------------------------------------------------------------------: | :---------------------------------------------------------------------------------------------------------------------------------------------------: | :---------------------------------------------------------------------------------------------------------------------------------------------------------------: |