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https://github.com/panoschatzi/erythrocyte_study_statistical_analyses

R code to process, analyze and visualize experimental data, as well as perform statistical analyses and simulations for our paper.
https://github.com/panoschatzi/erythrocyte_study_statistical_analyses

afex data-analysis emmeans ggplot2 lme4 purrr r rprogramming rstats rstudio statistics tidyverse visualization

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R code to process, analyze and visualize experimental data, as well as perform statistical analyses and simulations for our paper.

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README

        

## Erythrocyte glycolytic and redox metabolism affects muscle oxygenation and exercise performance: a randomized double-blind crossover study in humans

This repository corresponds to our paper, titled "**Erythrocyte glycolytic and redox metabolism affects muscle oxygenation and exercise performance: a randomized double-blind crossover study in humans**", where we investigated the role of erythrocyte redox metabolism in exercise fatigue using *in vivo*, *ex vivo* and computational analyses.

### Contact

- Panagiotis N. Chatzinikolaou
- Twitter handle:
- Personal website: [panos-chatz.netlify.app](https://panos-chatz.netlify.app/)
- Email: [chatzinpn\@phed-sr.auth.gr](mailto:[email protected])
- ORCID ID:

### Repository structure
- **analysis_docs/**
- Contains Quarto Markdown (`.qmd`) files documenting:
- `01_Data_Preparation.qmd`: Data cleaning, processing and reshaping from wide to long format for analysis.
- `02_Figures.qmd`: Code for visualizing the data in figures and panels.
- `03_Statistics.qmd`: Statistical analyses (repeated measures anova, post-hocs, parametric and non-parametric t-tests, and effect sizes).

- **data/**
- Includes raw and processed data files:
- `complete_database.csv`: Dataset in wide format in CSV.
- `tidyData.RData`: Data in tidy/long format.
- `README.md`: Documentation for the data files.

- **quantitative_analysis/**
- Scripts and results for quantitative analysis:
- `ODC plots.R`: R script for calculating p50 values and plotting Oxygen Dissociation Curves.
- `p50_analysis.R`: Statistical analysis of p50 values.

- **r_docs/**
- Custom helper functions for statistics:
- `MyCohensEffSizes.R`: Functions for calculating Cohen's effect sizes.
- `MyStatsFunctions.R`: Summary statistics functions.
- `README.md`: Documentation for the R scripts.

### License

This project uses a [CC-BY 4.0](http://creativecommons.org/licenses/by/4.0/) license. All code is additionally licensed under an [MIT license](https://github.com/PanosChatzi/Erythrocyte-Metabolism/blob/main/LICENSE).