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https://github.com/pingjunchen/thyroidrule

Rule-Based Thyroid Whole Slide Image Diagnosis
https://github.com/pingjunchen/thyroidrule

cnn-classification computational-pathology convolutional-neural-networks deep-learning deep-neural-networks patch-wise pytorch rule-based thyroid-cancer wsi

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Rule-Based Thyroid Whole Slide Image Diagnosis

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# Rule-based Automatic Diagnosis of Thyroid Nodules from Intraoperative Frozen Sections using Deep Learning
Frozen sections provide a basis for rapid intraoperative diagnosis that can guide surgery, but the diagnoses often challenge pathologists. Here we propose a rule-based system to differentiate thyroid nodules from intraoperative frozen sections using deep learning techniques. The proposed system consists of three components: (1) automatically locating tissue regions in the whole slide images (WSIs), (2) splitting located tissue regions into patches and classifying each patch into predefined categories using convolutional neural networks (CNN), and (3) integrating predictions of all patches to form the final diagnosis with a rule-based system. The simple flow chart of the proposed system is shown as below:
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### Citation
Please consider cite the paper if this repository facilitates your research.
```
@article{li2020rule,
title={Rule-based automatic diagnosis of thyroid nodules from intraoperative frozen sections using deep learning},
author={Li, Yuan and Chen, Pingjun and Li, Zhiyuan and Su, Hai and Yang, Lin and Zhong, Dingrong},
journal={Artificial Intelligence in Medicine},
volume={108},
pages={101918},
year={2020},
doi={https://doi.org/10.1016/j.artmed.2020.101918},
publisher={Elsevier}
}
```