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https://github.com/seungjae2525/mrmcbinary

Multi-Reader Multi-Case Analysis of Binary Diagnostic Tests
https://github.com/seungjae2525/mrmcbinary

binary-data diagnostic-accuracy mrmc

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Multi-Reader Multi-Case Analysis of Binary Diagnostic Tests

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# MRMCbinary

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# Multi-Reader Multi-Case Analysis of Binary Diagnostic Tests

## Description
This is the source code for the `MRMCbinary` package in R.
`MRMCbinary` is a package aimed at comparing the performance of diagnostic tests (i.e., sensitivity and specificity) for a binary outcome in multi-reader multi-case (MRMC) study.

### Reference
Lee, S., Jang, S., and Lee, W. Evaluating Diagnostic Accuracy of Binary Medical Tests in Multi-reader Multi-case Study.

## Installation
### The latest release version from CRAN:

```r
install.packages("MRMCbinary")
library(MRMCbinary)
```

### Current GitHub release:
Installation using R package `devtools`:

```r
if (!require("devtools")) { install.packages("devtools") } # if devtools not already installed
devtools::install_github("seungjae2525/MRMCbinary")
library(MRMCbinary)
```

## Example
This is a basic example which shows you how to use `MRMCbinary` package:

``` r
## Load MRMCbinary package
library(MRMCbinary)

## Load example data
data(VanDyke)

## Return the first parts of an object
head(VanDyke)

## Extract unique modalities
unique(VanDyke$treatment)

## Extract Unique readers
unique(VanDyke$reader)

## Create binary test results (Y_ijk)
VanDyke$Y <- as.numeric(VanDyke$rating >= 3)

## Example usage of MRMCbinary function:
# When comparing the sensitivities and specificities between modalities
modality_result <- MRMCbinary(data = VanDyke, Modality = treatment, Reader = reader,
Case = case, D = truth, Y = Y, measure = "All",
effect = "Modality", interaction = NULL,
reference.Modality = "1", reference.Reader = NULL)
print(modality_result)
summary(modality_result, digits = 3)

# When comparing the sensitivities and specificities between readers
reader_result <- MRMCbinary(data = VanDyke, Modality = treatment, Reader = reader,
Case = case, D = truth, Y = Y, measure = "All",
effect = "Reader", interaction = NULL,
reference.Modality = NULL, reference.Reader = "1")
print(reader_result)
summary(reader_result, digits = 3)

# When comparing the sensitivities and specificities between modalities and between readers together
# not considering interaction between modalities and readers
both_result_wo_int <- MRMCbinary(data = VanDyke, Modality = treatment, Reader = reader,
Case = case, D = truth, Y = Y, measure = "All",
effect = "Both", interaction = FALSE,
reference.Modality = "1", reference.Reader = "1")
print(both_result_wo_int)
summary(both_result_wo_int, digits = 3)

# When comparing the sensitivities and specificities between modalities and between readers together
# considering interaction between modalities and readers
both_result_with_int <- MRMCbinary(data = VanDyke, Modality = treatment, Reader = reader,
Case = case, D = truth, Y = Y, measure = "All",
effect = "Both", interaction = TRUE,
reference.Modality = "1", reference.Reader = "1")
print(both_result_with_int)
summary(both_result_with_int, digits = 3)
```

### Bug Reports:
You can also report bugs on GitHub under [Issues](https://github.com/seungjae2525/MRMCbinary/issues/).