https://github.com/sing-group/pandrugs-frontend
An AngularJS frontend for the PanDrugs application
https://github.com/sing-group/pandrugs-frontend
bioinformatics cancer database drugs personal-medicine
Last synced: 3 months ago
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An AngularJS frontend for the PanDrugs application
- Host: GitHub
- URL: https://github.com/sing-group/pandrugs-frontend
- Owner: sing-group
- License: gpl-3.0
- Created: 2017-08-28T18:36:29.000Z (about 8 years ago)
- Default Branch: master
- Last Pushed: 2024-11-28T16:30:44.000Z (10 months ago)
- Last Synced: 2024-11-28T17:29:46.242Z (10 months ago)
- Topics: bioinformatics, cancer, database, drugs, personal-medicine
- Language: HTML
- Homepage: http://www.pandrugs.org
- Size: 75.6 MB
- Stars: 3
- Watchers: 7
- Forks: 1
- Open Issues: 8
-
Metadata Files:
- Readme: README.md
- License: LICENSE
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README
# pandrugs-frontend
An AngularJS/Bootstrap frontend for the PanDrugs.
This project is generated with [yo angular generator](https://github.com/yeoman/generator-angular)
version 0.11.1.
## Project description
**PanDrugs** provides a platform **to guide the selection of therapies from the results of genome-wide studies in cancer
disease**.
Using 4 alternative inputs (e.g. standard VCF files, RNK files, gene list and drug query), **PanDrugs identify
actionable molecular alterations and prioritize drugs by calculating gene-drug scores** which takes into account:
i) genomic feature evidence by mutation impact score; ii) target pathway context; iii) drug approval status (FDA,
clinical trial or experimental small molecule inhibitors) and iv) manually-curated pharmacological information retrieved
from the literature.
**PanDrugs scores combines biological and clinical relevance of the genes and their susceptibility to be targeted**
reflecting the strength or evidence level of the gene-drug association in order to assist the clinical decision making.
PanDrugs current version integrates data from 18 primary sources and supports ~50,000 drug-target associations obtained
from ~6,000 genes and ~11,000 unique compounds.
## Build & development
Run `grunt` for building and `grunt serve` for preview.
## Testing
Running `grunt test` will run the unit tests with karma.